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CD35 抗体 (AA 420-550)

This 兔 多克隆 anti-CD35 antibody specifically detects CD35 in WB 和 IF. The antibody is reactive with 人 samples.
产品编号 ABIN6138990
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for CD35 抗体 (AA 420-550) (ABIN6138990)

抗原

See all CD35 (CR1) 抗体
CD35 (CR1) (Complement Component Receptor 1 (CD35) (CR1))

适用

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宿主

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克隆类型

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多克隆

标记

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This CD35 antibody is un-conjugated

应用范围

  • 75
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Western Blotting (WB), Immunofluorescence (IF)
  • 抗原表位

    • 15
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    • 1
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    AA 420-550

    序列

    FCPSPPVIPN GRHTGKPLEV FPFGKTVNYT CDPHPDRGTS FDLIGESTIR CTSDPQGNGV WSSPAPRCGI LGHCQAPDHF LFAKLKTQTN ASDFPIGTSL KYECRPEYYG RPFSITCLDN LVWSSPKDVC K

    交叉反应

    产品特性

    Polyclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 420-550 of human CD35/CD35/CR1 (NP_000642.3).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IF,1:50 - 1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    CD35 (CR1) (Complement Component Receptor 1 (CD35) (CR1))

    别名

    CR1

    背景

    This gene is a member of the receptors of complement activation (RCA) family and is located in the 'cluster RCA' region of chromosome 1. The gene encodes a monomeric single-pass type I membrane glycoprotein found on erythrocytes, leukocytes, glomerular podocytes, and splenic follicular dendritic cells. The Knops blood group system is a system of antigens located on this protein. The protein mediates cellular binding to particles and immune complexes that have activated complement. Decreases in expression of this protein and/or mutations in its gene have been associated with gallbladder carcinomas, mesangiocapillary glomerulonephritis, systemic lupus erythematosus and sarcoidosis. Mutations in this gene have also been associated with a reduction in Plasmodium falciparum rosetting, conferring protection against severe malaria. Alternate allele-specific splice variants, encoding different isoforms, have been characterized. Additional allele specific isoforms, including a secreted form, have been described but have not been fully characterized.,CR1,C3BR,C4BR,CD35,KN,Immunology & Inflammation,CD markers,Stem Cells,Hematopoietic Progenitors,CR1

    分子量

    223 kDa

    基因ID

    1378

    UniProt

    P17927

    途径

    Complement System, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Endopeptidase Activity
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