CPT1A 抗体 (AA 497-756)
Quick Overview for CPT1A 抗体 (AA 497-756) (ABIN6138976)
抗原
See all CPT1A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 497-756
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序列
- GYAEDGHCKG DINPNIPYPT RLQWDIPGEC QEVIETSLNT ANLLANDVDF HSFPFVAFGK GIIKKCRTSP DAFVQLALQL AHYKDMGKFC LTYEASMTRL FREGRTETVR SCTTESCDFV RAMVDPAQTV EQRLKLFKLA SEKHQHMYRL AMTGSGIDRH LFCLYVVSKY LAVESPFLKE VLSEPWRLST SQTPQQQVEL FDLENNPEYV SSGGGFGPVA DDGYGVSYIL VGENLINFHI SSKFSCPETG IISQGPSSDT
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 497-756 of human CPT1A (NP_001027017.1).
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000,IF,1:50 - 1:200,IP,1:50 - 1:100
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说明
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HIGH QUALITY
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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: "Regulation of AMPK-related glycolipid metabolism imbalances redox homeostasis and inhibits anchorage independent growth in human breast cancer cells." in: Redox biology, Vol. 17, pp. 180-191, (2018) (PubMed).
: "Oroxylin A suppresses the development and growth of colorectal cancer through reprogram of HIF1α-modulated fatty acid metabolism." in: Cell death & disease, Vol. 8, Issue 6, pp. e2865, (2018) (PubMed).
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: "Regulation of AMPK-related glycolipid metabolism imbalances redox homeostasis and inhibits anchorage independent growth in human breast cancer cells." in: Redox biology, Vol. 17, pp. 180-191, (2018) (PubMed).
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- CPT1A (Carnitine Palmitoyltransferase 1A (Liver) (CPT1A))
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别名
- CPT1A
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背景
- The mitochondrial oxidation of long-chain fatty acids is initiated by the sequential action of carnitine palmitoyltransferase I (which is located in the outer membrane and is detergent-labile) and carnitine palmitoyltransferase II (which is located in the inner membrane and is detergent-stable), together with a carnitine-acylcarnitine translocase. CPT I is the key enzyme in the carnitine-dependent transport across the mitochondrial inner membrane and its deficiency results in a decreased rate of fatty acid beta-oxidation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.,CPT1A,CPT1,CPT1-L,L-CPT1,Cancer,Signal Transduction,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial markers,Lipid Metabolism,AMPK Signaling Pathway,Endocrine and metabolic diseases,Obesity,Cardiovascular,Lipids,Fatty Acids,CPT1A
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分子量
- 86 kDa/88 kDa
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基因ID
- 1374
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UniProt
- P50416
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途径
- AMPK Signaling, Regulation of Lipid Metabolism by PPARalpha, Feeding Behaviour, Monocarboxylic Acid Catabolic Process
抗原
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