Claudin 16 抗体 (AA 50-150)
Quick Overview for Claudin 16 抗体 (AA 50-150) (ABIN6138679)
抗原
See all Claudin 16 (CLDN16) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 50-150
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序列
- HLSGARAGVC PCCHPDGLLA TMRDLLQYIA CFFAFFSAGF LIVATWTDCW MVNADDSLEV STKCRGLWWE CVTNAFDGIR TCDEYDSILA EHPLKLVVTR A
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交叉反应
- 人, 小鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- A synthetic peptide corresponding to a sequence within amino acids 50-150 of human CLDN16 (NP_006571.1).
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亚型
- IgG
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anti-Claudin 16 (CLDN16) (AA 1-73) antibody
CLDN16 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1F2 unconjugated
anti-Claudin 16 (CLDN16) (AA 1-73) antibodyCLDN16 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Claudin 16 (CLDN16) (AA 6-33), (N-Term) antibodyCLDN16 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB30098 unconjugated
anti-Claudin 16 (CLDN16) (AA 13-41), (N-Term) antibodyCLDN16 适用: 人 WB, FACS, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Claudin 16 (CLDN16) (AA 6-33) antibodyCLDN16 适用: 人 WB, FACS, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Claudin 16 (CLDN16) (C-Term) antibodyCLDN16 适用: 人, 小鼠, Cow, 犬, Pig, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Claudin 16 (CLDN16) (C-Term) antibodyCLDN16 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Claudin 16 (CLDN16) (C-Term) antibodyCLDN16 适用: 人, 小鼠, 大鼠, Cow, 犬, Pig, 马, 兔 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB,1:500 - 1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- Claudin 16 (CLDN16)
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别名
- CLDN16
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背景
- Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. It is found primarily in the kidneys, specifically in the thick ascending limb of Henle, where it acts as either an intercellular pore or ion concentration sensor to regulate the paracellular resorption of magnesium ions. Defects in this gene are a cause of primary hypomagnesemia, which is characterized by massive renal magnesium wasting with hypomagnesemia and hypercalciuria, resulting in nephrocalcinosis and renal failure. This gene and the CLDN1 gene are clustered on chromosome 3q28.,CLDN16,HOMG3,PCLN1,Signal Transduction,Cell Biology & Developmental Biology,Cell Adhesion,Tight Junctions,Cytoskeleton,CLDN16
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分子量
- 33 kDa
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基因ID
- 10686
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UniProt
- Q9Y5I7
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途径
- Hepatitis C
抗原
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