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Claudin 11 抗体 (AA 1-100)

This anti-Claudin 11 antibody is a 兔 多克隆 antibody detecting Claudin 11 in WB 和 IHC. Suitable for 人.
产品编号 ABIN6138675
发货至: 中国

Quick Overview for Claudin 11 抗体 (AA 1-100) (ABIN6138675)

抗原

See all Claudin 11 (CLDN11) 抗体
Claudin 11 (CLDN11)

适用

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宿主

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克隆类型

  • 38
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多克隆

标记

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This Claudin 11 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    AA 1-100

    序列

    MVATCLQVVG FVTSFVGWIG VIVTTSTNDW VVTCGYTIPT CRKLDELGSK GLWADCVMAT GLYHCKPLVD ILILPGYVQA CRALMIAASV LGLPAILLLL

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    A synthetic peptide corresponding to a sequence within amino acids 1-100 of human CLDN11 (NP_005593.2).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IHC,1:50 - 1:100

    说明

    HIGH QUALITY

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    Claudin 11 (CLDN11)

    别名

    CLDN11

    背景

    This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. The protein encoded by this gene is a major component of central nervous system (CNS) myelin and plays an important role in regulating proliferation and migration of oligodendrocytes. Mouse studies showed that the gene deficiency results in deafness and loss of the Sertoli cell epithelial phenotype in the testis. This protein is a tight junction protein at the human blood-testis barrier (BTB), and the BTB disruption is related to a dysfunction of this gene. Alternatively spliced transcript variants encoding different isoforms have been identified.,CLDN11,OSP,OTM,Immunology & Inflammation,Neuroscience,Cell Type Marker,Neurodegenerative Diseases,Oligodendrocyte marker,CLDN11

    分子量

    21 kDa

    基因ID

    5010

    UniProt

    O75508

    途径

    Hepatitis C
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