Claudin 11 抗体 (C-Term)
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北京 101111
Quick Overview for Claudin 11 抗体 (C-Term) (ABIN2778048)
抗原
See all Claudin 11 (CLDN11) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- CLDN11 Antibody - C-terminal region
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序列
- VSFGYSLYAG WIGAVLCLVG GCVILCCAGD AQAFGENRFY YTAGSSSPTH
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 86%, Rabbit: 100%, Rat: 86%
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产品特性
- This is a rabbit polyclonal antibody against CLDN11. It was validated on Western Blot and immunohistochemistry.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human CLDN11
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8097495
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- Claudin 11 (CLDN11)
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别名
- CLDN11
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背景
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Background Information: CLDN11 belongs to the claudin family of tight junction associated proteins and is a major component of central nervous system myelin that is necessary for normal CNS function. There is growing evidence that the protein determines the permeability between layers of myelin sheaths via focal adhesion and, with its expression highly regulated during development, may play an important role in cellular proliferation and migration. In addition, the protein is a candidate autoantigen in the development of autoimmune demyelinating disease.The protein encoded by this gene belongs to the claudin family of tight junction associated proteins and is a major component of central nervous system myelin that is necessary for normal CNS function. There is growing evidence that the protein determines the permeability between layers of myelin sheaths via focal adhesion and, with its expression highly regulated during development, may play an important role in cellular proliferation and migration. In addition, the protein is a candidate autoantigen in the development of autoimmune demyelinating disease.
Gene Name: Claudin 11
Alternative Symbols: OSP, OTM
Protein Name: Claudin-11
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分子量
- 22kDa
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基因ID
- 5010
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NCBI登录号
- NP_005593
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UniProt
- O75508
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途径
- Hepatitis C
抗原
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