CHM 抗体 (AA 120-210)
Quick Overview for CHM 抗体 (AA 120-210) (ABIN6138537)
抗原
See all CHM 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 120-210
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序列
- KNHALVTSAN STEAADSAFL PTEDESLSTM SCEMLTEQTP SSDPENALEV NGAEVTGEKE NHCDDKTCVP STSAEDMSEN VPIAEDTTEQ P
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交叉反应
- 人
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 120-210 of human CHM (NP_000381.1).
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000
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说明
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HIGH QUALITY
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- CHM (Choroideremia (Rab Escort Protein 1) (CHM))
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别名
- CHM
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背景
- This gene encodes component A of the RAB geranylgeranyl transferase holoenzyme. In the dimeric holoenzyme, this subunit binds unprenylated Rab GTPases and then presents them to the catalytic Rab GGTase subunit for the geranylgeranyl transfer reaction. Rab GTPases need to be geranylgeranyled on either one or two cysteine residues in their C-terminus to localize to the correct intracellular membrane. Mutations in this gene are a cause of choroideremia, also known as tapetochoroidal dystrophy (TCD). This X-linked disease is characterized by progressive dystrophy of the choroid, retinal pigment epithelium and retina. Alternatively spliced transcript variants have been found for this gene.,CHM,DXS540,GGTA,HSD-32,REP-1,TCD,Signal Transduction,Neuroscience,CHM
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分子量
- 12 kDa/73 kDa
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基因ID
- 1121
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UniProt
- P24386
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途径
- Sensory Perception of Sound
抗原
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