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CHM 抗体 (AA 120-210)

This anti-CHM antibody is a 兔 多克隆 antibody detecting CHM in WB. Suitable for 人.
产品编号 ABIN6138537
发货至: 中国

Quick Overview for CHM 抗体 (AA 120-210) (ABIN6138537)

抗原

See all CHM 抗体
CHM (Choroideremia (Rab Escort Protein 1) (CHM))

适用

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宿主

  • 27
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克隆类型

  • 28
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多克隆

标记

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This CHM antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    AA 120-210

    序列

    KNHALVTSAN STEAADSAFL PTEDESLSTM SCEMLTEQTP SSDPENALEV NGAEVTGEKE NHCDDKTCVP STSAEDMSEN VPIAEDTTEQ P

    交叉反应

    产品特性

    Polyclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 120-210 of human CHM (NP_000381.1).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000

    说明

    HIGH QUALITY

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    CHM (Choroideremia (Rab Escort Protein 1) (CHM))

    别名

    CHM

    背景

    This gene encodes component A of the RAB geranylgeranyl transferase holoenzyme. In the dimeric holoenzyme, this subunit binds unprenylated Rab GTPases and then presents them to the catalytic Rab GGTase subunit for the geranylgeranyl transfer reaction. Rab GTPases need to be geranylgeranyled on either one or two cysteine residues in their C-terminus to localize to the correct intracellular membrane. Mutations in this gene are a cause of choroideremia, also known as tapetochoroidal dystrophy (TCD). This X-linked disease is characterized by progressive dystrophy of the choroid, retinal pigment epithelium and retina. Alternatively spliced transcript variants have been found for this gene.,CHM,DXS540,GGTA,HSD-32,REP-1,TCD,Signal Transduction,Neuroscience,CHM

    分子量

    12 kDa/73 kDa

    基因ID

    1121

    UniProt

    P24386

    途径

    Sensory Perception of Sound
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