Cofilin 2 抗体 (AA 1-166)
Quick Overview for Cofilin 2 抗体 (AA 1-166) (ABIN6138465)
抗原
See all Cofilin 2 (CFL2) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 1-166
-
序列
- MASGVTVNDE VIKVFNDMKV RKSSTQEEIK KRKKAVLFCL SDDKRQIIVE EAKQILVGDI GDTVEDPYTS FVKLLPLNDC RYALYDATYE TKESKKEDLV FIFWAPESAP LKSKMIYASS KDAIKKKFTG IKHEWQVNGL DDIKDRSTLG EKLGGNVVVS LEGKPL
-
交叉反应
- 人, 小鼠, 大鼠
-
产品特性
- Polyclonal Antibodies
-
纯化方法
- Affinity purification
-
免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-166 of human CFL2 (NP_068733.1).
-
亚型
- IgG
-
-
-
-
应用备注
- WB,1:500 - 1:2000,IF,1:50 - 1:100
-
说明
-
HIGH QUALITY
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
-
-
- Cofilin 2 (CFL2)
-
别名
- CFL2
-
背景
- This gene encodes an intracellular protein that is involved in the regulation of actin-filament dynamics. This protein is a major component of intranuclear and cytoplasmic actin rods. It can bind G- and F-actin in a 1:1 ratio of cofilin to actin, and it reversibly controls actin polymerization and depolymerization in a pH -dependent manner. Mutations in this gene cause nemaline myopathy type 7, a form of congenital myopathy. Alternative splicing results in multiple transcript variants.,CFL2,NEM7,cofilin-2,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Microfilaments,Actins,TGF-b-Smad Signaling Pathway,CFL2
-
分子量
- 16 kDa/18 kDa
-
基因ID
- 1073
-
UniProt
- Q9Y281
-
途径
- Caspase Cascade in Apoptosis
抗原
-