Complement Factor B 抗体 (AA 80-420)
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北京 101111
Quick Overview for Complement Factor B 抗体 (AA 80-420) (ABIN6138446)
抗原
See all Complement Factor B (CFB) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 80-420
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序列
- GSWSTLKTQD QKTVRKAECR AIHCPRPHDF ENGEYWPRSP YYNVSDEISF HCYDGYTLRG SANRTCQVNG RWSGQTAICD NGAGYCSNPG IPIGTRKVGS QYRLEDSVTY HCSRGLTLRG SQRRTCQEGG SWSGTEPSCQ DSFMYDTPQE VAEAFLSSLT ETIEGVDAED GHGPGEQQKR KIVLDPSGSM NIYLVLDGSD SIGASNFTGA KKCLVNLIEK VASYGVKPRY GLVTYATYPK IWVKVSEADS SNADWVTKQL NEINYEDHKL KSGTNTKKAL QAVYSMMSWP DDVPPEGWNR TRHVIILMTD GLHNMGGDPI TVIDEIRDLL YIGKDRKNPR E
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交叉反应
- 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 80-420 of human CFB (NP_001701.2).
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亚型
- IgG
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anti-Complement Factor B (CFB) (AA 474-590) antibody
CFB 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Complement Factor B (CFB) (AA 34-159) antibodyCFB 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Complement Factor B (CFB) antibodyCFB 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Complement Factor B (CFB) antibodyCFB 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Complement Factor B (CFB) (AA 26-751) antibodyCFB 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Complement Factor B (CFB) antibodyCFB 适用: 人 IHC (p), ID 宿主: 山羊 Polyclonal unconjugated
anti-Complement Factor B (CFB) (AA 35-160) antibodyCFB 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Complement Factor B (CFB) (AA 301-400) antibodyCFB 适用: 小鼠, 大鼠 WB, ELISA, IHC (p), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-Complement Factor B (CFB) (AA 32-157) antibodyCFB 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Complement Factor B (CFB) (AA 269-382) antibodyCFB 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB,1:1000 - 1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- Complement Factor B (CFB)
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别名
- CFB
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背景
- This gene encodes complement factor B, a component of the alternative pathway of complement activation. Factor B circulates in the blood as a single chain polypeptide. Upon activation of the alternative pathway, it is cleaved by complement factor D yielding the noncatalytic chain Ba and the catalytic subunit Bb. The active subunit Bb is a serine protease which associates with C3b to form the alternative pathway C3 convertase. Bb is involved in the proliferation of preactivated B lymphocytes, while Ba inhibits their proliferation. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. This cluster includes several genes involved in regulation of the immune reaction. Polymorphisms in this gene are associated with a reduced risk of age-related macular degeneration. The polyadenylation site of this gene is 421 bp from the 5' end of the gene for complement component 2.,CFB,AHUS4,ARMD14,BF,BFD,CFAB,CFBD,FB,FBI12,GBG,H2-Bf,PBF2,Immunology & Inflammation,Cell Intrinsic Innate Immunity Signaling Pathway,CFB
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分子量
- 68 kDa/85 kDa
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基因ID
- 629
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UniProt
- P00751
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途径
- Complement System, Proton Transport, Ribonucleoside Biosynthetic Process
抗原
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