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CDK8 抗体 (AA 365-464)

This anti-CDK8 antibody is a 兔 多克隆 antibody detecting CDK8 in WB 和 IP. Suitable for 人.
产品编号 ABIN6138329
发货至: 中国

Quick Overview for CDK8 抗体 (AA 365-464) (ABIN6138329)

抗原

See all CDK8 抗体
CDK8 (Cyclin-Dependent Kinase 8 (CDK8))

适用

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宿主

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克隆类型

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多克隆

标记

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This CDK8 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunoprecipitation (IP)
  • 抗原表位

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    AA 365-464

    序列

    DDKGDKKNQQ QQQGNNHTNG TGHPGNQDSS HTQGPPLKKV RVVPPTTTSG GLIMTSDYQR SNPHAAYPNP GPSTSQPQSS MGYSATSQQP PQYSHQTHRY

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 365-464 of human CDK8 (NP_001251.1).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IP,1:50 - 1:100

    说明

    HIGH QUALITY

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    CDK8 (Cyclin-Dependent Kinase 8 (CDK8))

    别名

    CDK8

    背景

    This gene encodes a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are known to be important regulators of cell cycle progression. This kinase and its regulatory subunit, cyclin C, are components of the Mediator transcriptional regulatory complex, involved in both transcriptional activation and repression by phosphorylation of the carboxy-terminal domain of the largest subunit of RNA polymerase II. This kinase regulates transcription by targeting the cyclin-dependent kinase 7 subunits of the general transcription initiation factor IIH, thus providing a link between the Mediator complex and the basal transcription machinery. Multiple pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants.,CDK8,K35,Epigenetics & Nuclear Signaling,Signal Transduction,Kinase,Serine/threonine kinases,Cell Biology & Developmental Biology,Cell Cycle,Notch Signaling Pathway,Wnt/β-Catenin Signaling Pathway,CDK8

    分子量

    53 kDa

    基因ID

    1024

    UniProt

    P49336

    途径

    Cell Division Cycle, Regulation of Lipid Metabolism by PPARalpha
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