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CD74 抗体 (AA 73-232)

This anti-CD74 antibody is a 兔 多克隆 antibody detecting CD74 in WB 和 IF. Suitable for 人.
产品编号 ABIN6138228
发货至: 中国

Quick Overview for CD74 抗体 (AA 73-232) (ABIN6138228)

抗原

See all CD74 抗体
CD74 (HLA-DR-gamma (CD74))

适用

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宿主

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克隆类型

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多克隆

标记

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This CD74 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF)
  • 抗原表位

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    AA 73-232

    序列

    QQQGRLDKLT VTSQNLQLEN LRMKLPKPPK PVSKMRMATP LLMQALPMGA LPQGPMQNAT KYGNMTEDHV MHLLQNADPL KVYPPLKGSF PENLRHLKNT METIDWKVFE SWMHHWLLFE MSRHSLEQKP TDAPPKESLE LEDPSSGLGV TKQDLGPVPM

    交叉反应

    人, 大鼠

    产品特性

    Polyclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 73-232 of human CD74 (NP_004346.1).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IF,1:50 - 1:200

    说明

    HIGH QUALITY

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    CD74 (HLA-DR-gamma (CD74))

    别名

    CD74

    背景

    The protein encoded by this gene associates with class II major histocompatibility complex (MHC) and is an important chaperone that regulates antigen presentation for immune response. It also serves as cell surface receptor for the cytokine macrophage migration inhibitory factor (MIF) which, when bound to the encoded protein, initiates survival pathways and cell proliferation. This protein also interacts with amyloid precursor protein (APP) and suppresses the production of amyloid beta (Abeta). Multiple alternatively spliced transcript variants encoding different isoforms have been identified.,CD74,DHLAG,HLADG,II,Ia-GAMMA,Cell Biology & Developmental Biology,Apoptosis,Immunology & Inflammation,CD markers,CD74

    分子量

    18 kDa/26 kDa/33 kDa

    基因ID

    972

    UniProt

    P04233

    途径

    Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Negative Regulation of intrinsic apoptotic Signaling, Cancer Immune Checkpoints
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