CD163 抗体 (AA 750-1050)
Quick Overview for CD163 抗体 (AA 750-1050) (ABIN6138118)
抗原
See all CD163 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 750-1050
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序列
- LSDAHVVCRQ LGCGEAINAT GSAHFGEGTG PIWLDEMKCN GKESRIWQCH SHGWGQQNCR HKEDAGVICS EFMSLRLTSE ASREACAGRL EVFYNGAWGT VGKSSMSETT VGVVCRQLGC ADKGKINPAS LDKAMSIPMW VDNVQCPKGP DTLWQCPSSP WEKRLASPSE ETWITCDNKI RLQEGPTSCS GRVEIWHGGS WGTVCDDSWD LDDAQVVCQQ LGCGPALKAF KEAEFGQGTG PIWLNEVKCK GNESSLWDCP ARRWGHSECG HKEDAAVNCT DISVQKTPQK ATTGRSSRQS S
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 750-1050 of human CD163 (NP_004235.4).
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亚型
- IgG
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应用备注
- WB,1:500 - 1:1000,IHC,1:50 - 1:200,IF,1:50 - 1:200
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说明
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HIGH QUALITY
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- CD163
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别名
- CD163
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背景
- The protein encoded by this gene is a member of the scavenger receptor cysteine-rich (SRCR) superfamily, and is exclusively expressed in monocytes and macrophages. It functions as an acute phase-regulated receptor involved in the clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages, and may thereby protect tissues from free hemoglobin-mediated oxidative damage. This protein may also function as an innate immune sensor for bacteria and inducer of local inflammation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.,CD163,M130,MM130,SCARI1,Immunology & Inflammation,CD markers,Cell Intrinsic Innate Immunity Signaling Pathway,Cardiovascular,CD163
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分子量
- 121 kDa/124 kDa/125 kDa
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基因ID
- 9332
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UniProt
- Q86VB7
抗原
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