Calmodulin 2 抗体 (AA 1-149)
Quick Overview for Calmodulin 2 抗体 (AA 1-149) (ABIN6137872)
抗原
See all Calmodulin 2 (CALM2) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-149
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序列
- MADQLTEEQI AEFKEAFSLF DKDGDGTITT KELGTVMRSL GQNPTEAELQ DMINEVDADG NGTIDFPEFL TMMARKMKDT DSEEEIREAF RVFDKDGNGY ISAAELRHVM TNLGEKLTDE EVDEMIREAD IDGDGQVNYE EFVQMMTAK
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交叉反应
- 人, 小鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-149 of human CALM2 (NP_001734.1).
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亚型
- IgG
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anti-Calmodulin 2 (CALM2) (AA 1-149) antibody
CALM2 适用: 人 WB, IF, ELISA 宿主: 小鼠 Monoclonal 3F4-G5 unconjugated
anti-Calmodulin 2 (CALM2) (AA 1-149) antibodyCALM2 适用: 人 WB, IF, ELISA, FACS, ICC 宿主: 小鼠 Monoclonal J4D8 unconjugated
anti-Calmodulin 2 (CALM2) antibodyCALM2 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Calmodulin 2 (CALM2) (AA 1-149) antibodyCALM2 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Calmodulin 2 (CALM2) antibodyCALM2 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB,1:500 - 1:2000
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说明
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HIGH QUALITY
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- Calmodulin 2 (CALM2)
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别名
- CALM2
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背景
- This gene is a member of the calmodulin gene family. There are three distinct calmodulin genes dispersed throughout the genome that encode the identical protein, but differ at the nucleotide level. Calmodulin is a calcium binding protein that plays a role in signaling pathways, cell cycle progression and proliferation. Several infants with severe forms of long-QT syndrome (LQTS) who displayed life-threatening ventricular arrhythmias together with delayed neurodevelopment and epilepsy were found to have mutations in either this gene or another member of the calmodulin gene family (PMID:23388215). Mutations in this gene have also been identified in patients with less severe forms of LQTS (PMID:24917665), while mutations in another calmodulin gene family member have been associated with catecholaminergic polymorphic ventricular tachycardia (CPVT)(PMID:23040497), a rare disorder thought to be the cause of a significant fraction of sudden cardiac deaths in young individuals. Pseudogenes of this gene are found on chromosomes 10, 13, and 17. Alternative splicing results in multiple transcript variants encoding different isoforms.,CALM2,CAMII,LQT15,PHKD,PHKD2,caM,Signal Transduction,Kinase,ErbB-HER Signaling Pathway,Cell Biology & Developmental Biology,Cell Cycle,Centrosome,Cytoskeleton,Actins,Immunology & Inflammation,B Cell Receptor Signaling Pathway,T Cell Receptor Signaling Pathway,Neuroscience,Neurodegenerative Diseases,CALM2
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分子量
- 17 kDa
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基因ID
- 805
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UniProt
- P62158
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途径
- RTK signaling, Interferon-gamma Pathway, Fc-epsilon Receptor Signaling Pathway, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Cellular Glucan Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, G-protein mediated Events, Signaling Events mediated by VEGFR1 and VEGFR2, Interaction of EGFR with phospholipase C-gamma, Phototransduction, Negative Regulation of Transporter Activity, VEGFR1 Specific Signals, BCR Signaling
抗原
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