C4BPB 抗体 (AA 18-251)
Quick Overview for C4BPB 抗体 (AA 18-251) (ABIN6137775)
抗原
See all C4BPB 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 18-251
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序列
- SDEHCPELPP VDNSIFVAKE VEGQILGTYV CIKGYHLVGK KTLFCNASKE WDNTTTECRL GHCPDPVLVN GEFSSSGPVN VSDKITFMCN DHYILKGSNR SQCLEDHTWA PPFPICKSRD CDPPGNPVHG YFEGNNFTLG STISYYCEDR YYLVGVQEQQ CVDGEWSSAL PVCKLIQEAP KPECEKALLA FQESKNLCEA MENFMQQLKE SGMTMEELKY SLELKKAELK AKLL
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 18-251 of human C4BPB (NP_001017364.1).
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000
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说明
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HIGH QUALITY
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- C4BPB (Complement Component 4 Binding Protein, beta (C4BPB))
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别名
- C4BPB
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背景
- This gene encodes a member of a superfamily of proteins composed predominantly of tandemly arrayed short consensus repeats of approximately 60 amino acids. A single, unique beta-chain encoded by this gene assembles with seven identical alpha-chains into the predominant isoform of C4b-binding protein, a multimeric protein that controls activation of the complement cascade through the classical pathway. C4b-binding protein has a regulatory role in the coagulation system also, mediated through the beta-chain binding of protein S, a vitamin K-dependent protein that serves as a cofactor of activated protein C. The genes encoding both alpha and beta chains are located adjacent to each other on human chromosome 1 in the regulator of complement activation gene cluster. Alternative splicing gives rise to multiple transcript variants.,C4BPB,C4BP,Immunology & Inflammation,Cell Intrinsic Innate Immunity Signaling Pathway,C4BPB
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分子量
- 28 kDa
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基因ID
- 725
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UniProt
- P20851
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途径
- Complement System
抗原
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