BTK 抗体 (AA 173-272)
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- 抗原 See all BTK 抗体
- BTK (Bruton Agammaglobulinemia tyrosine Kinase (BTK))
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抗原表位
- AA 173-272
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This BTK antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 序列
- GSLKPGSSHR KTKKPLPPTP EEDQILKKPL PPEPAAAPVS TSELKKVVAL YDYMPMNAND LQLRKGDEYF ILEESNLPWW RARDKNGQEG YIPSNYVTEA
- 交叉反应
- 人, 小鼠, 大鼠
- 产品特性
- Polyclonal Antibodies
- 纯化方法
- Affinity purification
- 免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 173-272 of human BTK (NP_000052.1).
- 亚型
- IgG
- Top Product
- Discover our top product BTK Primary Antibody
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- 应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:200
- 说明
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HIGH QUALITY
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- BTK (Bruton Agammaglobulinemia tyrosine Kinase (BTK))
- 别名
- BTK (BTK 产品)
- 别名
- BTK antibody, atk antibody, bpk antibody, xla antibody, imd1 antibody, agmx1 antibody, psctk1 antibody, AGMX1 antibody, AT antibody, ATK antibody, BPK antibody, IMD1 antibody, PSCTK1 antibody, XLA antibody, AI528679 antibody, xid antibody, Bruton tyrosine kinase antibody, Bruton agammaglobulinemia tyrosine kinase antibody, BTK antibody, btk antibody, Btk antibody
- 背景
- The protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. Alternative splicing results in multiple transcript variants encoding different isoforms.,AGMX1,AT,ATK,BPK,IMD1,PSCTK1,XLA,BTK,Signal Transduction,Kinase,Tyrosine kinases,Cell Biology & Developmental Biology,Apoptosis,Immunology & Inflammation,B Cell Receptor Signaling Pathway,Toll-like Receptor Signaling Pathway,Cell Intrinsic Innate Immunity Signaling Pathway,TLR Signaling,BTK
- 分子量
- 76 kDa/79 kDa
- 基因ID
- 695
- UniProt
- Q06187
- 途径
- Fc-epsilon Receptor Signaling Pathway, Hormone Transport, Activation of Innate immune Response, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades, BCR Signaling
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