BMP15 抗体 (AA 143-392)
Quick Overview for BMP15 抗体 (AA 143-392) (ABIN6137593)
抗原
See all BMP15 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 143-392
-
序列
- LTRFNLSCHV EPWVQKNPTN HFPSSEGDSS KPSLMSNAWK EMDITQLVQQ RFWNNKGHRI LRLRFMCQQQ KDSGGLELWH GTSSLDIAFL LLYFNDTHKS IRKAKFLPRG MEEFMERESL LRRTRQADGI SAEVTASSSK HSGPENNQCS LHPFQISFRQ LGWDHWIIAP PFYTPNYCKG TCLRVLRDGL NSPNHAIIQN LINQLVDQSV PRPSCVPYKY VPISVLMIEA NGSILYKEYE GMIAESCTCR
-
交叉反应
- 人, 小鼠, 大鼠
-
产品特性
- Polyclonal Antibodies
-
纯化方法
- Affinity purification
-
免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 143-392 of human BMP15 (NP_005439.2).
-
亚型
- IgG
-
-
-
-
应用备注
- WB,1:500 - 1:2000,IF,1:50 - 1:100
-
说明
-
HIGH QUALITY
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
-
-
- BMP15 (Bone Morphogenetic Protein 15 (BMP15))
-
别名
- BMP15
-
背景
- This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate subunits of a disulfide-linked homodimer, or alternatively, a heterodimer, with the related protein, growth differentiation factor 9 (GDF9). This protein plays a role in oocyte maturation and follicular development, through activation of granulosa cells. Defects in this gene are the cause of ovarian dysgenesis and are associated with premature ovarian failure.,BMP15,GDF9B,ODG2,POF4,Signal Transduction,Cell Biology & Developmental Biology,Growth factor,Wnt/β-Catenin Signaling Pathway,Immunology & Inflammation,Cytokines,NF-kB Signaling Pathway,Stem Cells,Germline Stem Cells,Cardiovascular,Angiogenesis,BMP15
-
分子量
- 45 kDa
-
基因ID
- 9210
-
UniProt
- O95972
抗原
-