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BBS10 抗体 (AA 474-723)

This anti-BBS10 antibody is a 兔 多克隆 antibody detecting BBS10 in WB. Suitable for 人.
产品编号 ABIN6137466
发货至: 中国

Quick Overview for BBS10 抗体 (AA 474-723) (ABIN6137466)

抗原

See all BBS10 抗体
BBS10 (Bardet-Biedl Syndrome 10 (BBS10))

适用

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宿主

  • 40
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克隆类型

  • 41
多克隆

标记

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This BBS10 antibody is un-conjugated

应用范围

  • 31
  • 15
  • 13
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  • 9
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Western Blotting (WB)
  • 抗原表位

    • 15
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    AA 474-723

    序列

    AENKDALEKT QTYLKVHSNL VIPDVELETY IPYSTPTLTP TDTFQTVETL TCLSLERNRL TDYYEPLLKN NSTAYSTRGN RIEISYENLQ VTNITRKGSM LPVSCKLPNM GTSQSYLSSS MPAGCVLPVG GNFEILLHYY LLNYAKKCHQ SEETMVSMII ANALLGIPKV LYKSKTGKYS FPHTYIRAVH ALQTNQPLVS SQTGLESVMG KYQLLTSVLQ CLTKILTIDM VITVKRHPQK VHNQDSEDEL

    交叉反应

    人, 小鼠

    产品特性

    Polyclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 474-723 of human BBS10 (NP_078961.3).

    亚型

    IgG
  • 应用备注

    WB,1:200 - 1:3000

    说明

    HIGH QUALITY

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    BBS10 (Bardet-Biedl Syndrome 10 (BBS10))

    别名

    BBS10

    背景

    This gene is a member of the Bardet-Biedl syndrome (BBS) gene family. Bardet-Biedl syndrome is an autosomal recessive disorder characterized by progressive retinal degeneration, obesity, polydactyly, renal malformation and mental retardation. The proteins encoded by BBS gene family members are structurally diverse and the similar phenotypes exhibited by mutations in BBS gene family members is likely due to their shared roles in cilia formation and function. Many BBS proteins localize to the basal bodies, ciliary axonemes, and pericentriolar regions of cells. BBS proteins may also be involved in intracellular trafficking via microtubule-related transport. The protein encoded by this gene is likely not a ciliary protein but rather has distant sequence homology to type II chaperonins. As a molecular chaperone, this protein may affect the folding or stability of other ciliary or basal body proteins. Inhibition of this protein's expression impairs ciliogenesis in preadipocytes. Mutations in this gene cause Bardet-Biedl syndrome type 10.,BBS10,C12orf58,Epigenetics & Nuclear Signaling,Transcription Factors,Neuroscience,BBS10

    分子量

    80 kDa

    基因ID

    79738

    UniProt

    Q8TAM1
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