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BBS10 抗体 (C-Term)

BBS10 适用: 人, 兔 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2788220
发货至: 中国
  • 抗原 See all BBS10 抗体
    BBS10 (Bardet-Biedl Syndrome 10 (BBS10))
    抗原表位
    • 15
    • 8
    • 7
    • 6
    • 4
    • 2
    • 1
    • 1
    C-Term
    适用
    • 39
    • 2
    • 1
    人, 兔
    宿主
    • 38
    • 1
    克隆类型
    • 39
    多克隆
    标记
    • 12
    • 4
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This BBS10 antibody is un-conjugated
    应用范围
    • 35
    • 20
    • 13
    • 13
    • 13
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB)
    序列
    SQTGLESVMG KYQLLTSVLQ CLTKILTIDM VITVKRHPQK VHNQDSEDEL
    预测反应
    Human: 100%, Rabbit: 86%
    产品特性
    This is a rabbit polyclonal antibody against BBS10. It was validated on Western Blot.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the C terminal region of human BBS10
    Top Product
    Discover our top product BBS10 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 723 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    BBS10 (Bardet-Biedl Syndrome 10 (BBS10))
    别名
    BBS10 (BBS10 产品)
    别名
    MGC84945 antibody, si:dkey-30c15.16 antibody, C12orf58 antibody, RGD1560748 antibody, 1300007O09Rik antibody, AI452285 antibody, Bardet-Biedl syndrome 10 antibody, Bardet-Biedl syndrome 10 L homeolog antibody, Bardet-Biedl syndrome 10 (human) antibody, BBS10 antibody, bbs10.L antibody, bbs10 antibody, Bbs10 antibody
    背景
    This gene is a member of the Bardet-Biedl syndrome (BBS) gene family. Bardet-Biedl syndrome is an autosomal recessive disorder characterized by progressive retinal degeneration, obesity, polydactyly, renal malformation and mental retardation. The proteins encoded by BBS gene family members are structurally diverse and the similar phenotypes exhibited by mutations in BBS gene family members is likely due to their shared roles in cilia formation and function. Many BBS proteins localize to the basal bodies, ciliary axonemes, and pericentriolar regions of cells. BBS proteins may also be involved in intracellular trafficking via microtubule-related transport. The protein encoded by this gene is likely not a ciliary protein but rather has distant sequence homology to type II chaperonins. As a molecular chaperone, this protein may affect the folding or stability of other ciliary or basal body proteins. Inhibition of this protein's expression impairs ciliogenesis in preadipocytes. Mutations in this gene cause Bardet-Biedl syndrome type 10.
    Alias Symbols: C12orf58, FLJ23560
    Protein Interaction Partner: UBC, YAE1D1, MAPK8IP2, HDAC6, TNFSF11, MAP3K7, RGS2, RASA1, PTK2, MAPK6, NR4A1, FRZB, CSNK1E,
    Protein Size: 723
    分子量
    81 kDa
    基因ID
    79738
    NCBI登录号
    NM_024685, NP_078961
    UniProt
    Q8TAM1
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