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Amphiregulin 抗体 (AA 20-252)

This anti-Amphiregulin antibody is a 兔 多克隆 antibody detecting Amphiregulin in WB, IHC 和 IF. Suitable for 人.
产品编号 ABIN6137065
发货至: 中国

Quick Overview for Amphiregulin 抗体 (AA 20-252) (ABIN6137065)

抗原

See all Amphiregulin (AREG) 抗体
Amphiregulin (AREG)

适用

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宿主

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克隆类型

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多克隆

标记

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This Amphiregulin antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 抗原表位

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    AA 20-252

    序列

    SGHYAAGLDL NDTYSGKREP FSGDHSADGF EVTSRSEMSS GSEISPVSEM PSSSEPSSGA DYDYSEEYDN EPQIPGYIVD DSVRVEQVVK PPQNKTESEN TSDKPKRKKK GGKNGKNRRN RKKKNPCNAE FQNFCIHGEC KYIEHLEAVT CKCQQEYFGE RCGEKSMKTH SMIDSSLSKI ALAAIAAFMS AVILTAVAVI TVQLRRQYVR KYEGEAEERK KLRQENGNVH AIA

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 20-252 of human AREG (NP_001648.1).

    亚型

    IgG
  • 应用备注

    WB,1:1000 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

    说明

    HIGH QUALITY

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    Amphiregulin (AREG)

    别名

    AREG

    背景

    The protein encoded by this gene is a member of the epidermal growth factor family. It is an autocrine growth factor as well as a mitogen for astrocytes, Schwann cells and fibroblasts. It is related to epidermal growth factor (EGF) and transforming growth factor alpha (TGF-alpha). The protein interacts with the EGF/TGF-alpha receptor to promote the growth of normal epithelial cells, and it inhibits the growth of certain aggressive carcinoma cell lines. It also functions in mammary gland, oocyte and bone tissue development. This gene is associated with a psoriasis-like skin phenotype, and is also associated with other pathological disorders, including various types of cancers and inflammatory conditions.,AREG,AR,AREGB,CRDGF,SDGF,amphiregulin,Signal Transduction,ErbB-HER Signaling Pathway,Cell Biology & Developmental Biology,Growth factor,Immunology & Inflammation,Cytokines,AREG

    分子量

    27 kDa

    基因ID

    374

    UniProt

    P15514

    途径

    RTK signaling, EGFR Signaling Pathway
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