APLP1 抗体 (AA 39-300)
Quick Overview for APLP1 抗体 (AA 39-300) (ABIN6136993)
抗原
See all APLP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 39-300
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序列
- SLAGGSPGAA EAPGSAQVAG LCGRLTLHRD LRTGRWEPDP QRSRRCLRDP QRVLEYCRQM YPELQIARVE QATQAIPMER WCGGSRSGSC AHPHHQVVPF RCLPGEFVSE ALLVPEGCRF LHQERMDQCE SSTRRHQEAQ EACSSQGLIL HGSGMLLPCG SDRFRGVEYV CCPPPGTPDP SGTAVGDPST RSWPPGSRVE GAEDEEEEES FPQPVDDYFV EPPQAEEEEE TVPPPSSHTL AVVGKVTPTP RPTDGVDIYF GM
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 39-300 of human APLP1 (NP_005157.1).
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:10 - 1:100
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说明
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HIGH QUALITY
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- APLP1 (Amyloid beta (A4) Precursor-Like Protein 1 (APLP1))
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别名
- APLP1
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背景
- This gene encodes a member of the highly conserved amyloid precursor protein gene family. The encoded protein is a membrane-associated glycoprotein that is cleaved by secretases in a manner similar to amyloid beta A4 precursor protein cleavage. This cleavage liberates an intracellular cytoplasmic fragment that may act as a transcriptional activator. The encoded protein may also play a role in synaptic maturation during cortical development. Alternatively spliced transcript variants encoding different isoforms have been described.,APLP1,APLP,Cell Biology & Developmental Biology,Apoptosis,Neuroscience,Neurodegenerative Diseases,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease,APLP1
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分子量
- 72 kDa
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基因ID
- 333
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UniProt
- P51693
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途径
- cAMP Metabolic Process
抗原
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