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ACOX1 抗体 (AA 1-270)

This anti-ACOX1 antibody is a 兔 多克隆 antibody detecting ACOX1 in WB, IHC 和 IF. Suitable for 人. This Primary Antibody has been cited in 2+ publications.
产品编号 ABIN6136442
发货至: 中国

Quick Overview for ACOX1 抗体 (AA 1-270) (ABIN6136442)

抗原

See all ACOX1 抗体
ACOX1 (Acyl-CoA Oxidase 1, Palmitoyl (ACOX1))

适用

  • 57
  • 21
  • 3

宿主

  • 52
  • 6

克隆类型

  • 46
  • 12
多克隆

标记

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This ACOX1 antibody is un-conjugated

应用范围

  • 41
  • 34
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Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 抗原表位

    • 8
    • 8
    • 5
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    AA 1-270

    序列

    MNPDLRRERD SASFNPELLT HILDGSPEKT RRRREIENMI LNDPDFQHED LNFLTRSQRY EVAVRKSAIM VKKMREFGIA DPDEIMWFKN FVHRGRPEPL DLHLGMFLPT LLHQATAEQQ ERFFMPAWNL EIIGTYAQTE MGHGTHLRGL ETTATYDPET QEFILNSPTV TSIKWWPGGL GKTSNHAIVL AQLITKGKCY GLHAFIVPIR EIGTHKPLPG ITVGDIGPKF GYDEIDNGYL KMDNHRIPRE NMLMKYAQVK PDGTYVKPLS

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human ACOX1 (NP_004026.2).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IHC,1:100 - 1:200,IF,1:50 - 1:200

    说明

    HIGH QUALITY

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • Yan, Li, Peng, Long, Fan, Wang, Shi, Xie, Zhao, Yan: "The Fatty Acid β-Oxidation Pathway is Activated by Leucine Deprivation in HepG2 Cells: A Comparative Proteomics Study." in: Scientific reports, Vol. 7, Issue 1, pp. 1914, (2018) (PubMed).

    Long, Muhamad, Yan, Yu, Fan, Wang, Li, Purnomoadi, Achmadi, Yan: "Quantitative proteomics analysis reveals glutamine deprivation activates fatty acid β-oxidation pathway in HepG2 cells." in: Amino acids, Vol. 48, Issue 5, pp. 1297-307, (2017) (PubMed).

  • 抗原

    ACOX1 (Acyl-CoA Oxidase 1, Palmitoyl (ACOX1))

    别名

    ACOX1

    背景

    The protein encoded by this gene is the first enzyme of the fatty acid beta-oxidation pathway, which catalyzes the desaturation of acyl-CoAs to 2-trans-enoyl-CoAs. It donates electrons directly to molecular oxygen, thereby producing hydrogen peroxide. Defects in this gene result in pseudoneonatal adrenoleukodystrophy, a disease that is characterized by accumulation of very long chain fatty acids. Alternatively spliced transcript variants encoding different isoforms have been identified.,ACOX1,ACOX,PALMCOX,SCOX,Cancer,Signal Transduction,Endocrine & Metabolism,Lipid Metabolism,Cardiovascular,Lipids,Fatty Acids,ACOX1

    分子量

    70 kDa/74 kDa

    基因ID

    51

    UniProt

    Q15067

    途径

    Regulation of Lipid Metabolism by PPARalpha, Monocarboxylic Acid Catabolic Process
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