TYK2 抗体 (pTyr1054, pTyr1055)
Our Local Distributor
北京 101111
Quick Overview for TYK2 抗体 (pTyr1054, pTyr1055) (ABIN6136278)
抗原
See all TYK2 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- pTyr1054, pTyr1055
-
序列
- EYYR
-
交叉反应
- 小鼠, 大鼠
-
产品特性
- Phosphorylated Antibodies
-
免疫原
- A synthetic phosphorylated peptide around Y1054 & Y1055 of human Tyk2 (NP_003322.3).
-
亚型
- IgG
-
-
-
-
应用备注
- WB,1:500 - 1:1000
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
-
-
- TYK2 (Tyrosine Kinase 2 (TYK2))
-
别名
- Tyk2
-
背景
- This gene encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E.,TYK2,IMD35,JTK1,Signal Transduction,Kinase,Tyrosine kinases,ErbB-HER Signaling Pathway,Immunology & Inflammation,Protein phosphorylation,Tyk2
-
分子量
- 133 kDa
-
基因ID
- 7297
-
UniProt
- P29597
-
途径
- JAK/STAT Signaling, Hepatitis C
抗原
-