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Caspase 3 抗体

This 兔 多克隆 anti-Caspase 3 antibody specifically detects Caspase 3 in WB 和 ELISA. The antibody is reactive with 人 和 猴 samples.
产品编号 ABIN5960895
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Caspase 3 抗体 (ABIN5960895)

抗原

See all Caspase 3 (CASP3) 抗体
Caspase 3 (CASP3)

适用

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人, 猴

宿主

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克隆类型

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多克隆

标记

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This Caspase 3 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
  • 特异性

    A830040C14Rik,Apopain,CASP-3,CASP3,CASP3,Casp3a,Caspase 3,Caspase 3,apoptosis-related cysteine peptidase,Caspase 3,apoptosis-related cysteine protease,Caspase 3,apoptosis-related cysteine protease a,Caspase-3 subunit p12,CC3,CPP-32,CPP32,CPP32B,Cysteine protease CPP32,EC 3.4.22.56,LICE,mldy,OTTHUMP00000165052,OTTHUMP00000165053,OTTHUMP00000165054,PARP cleavage protease,Procaspase3,Protein Yama,SCA 1,SCA-1,SREBP cleavage activity 1,Yama

    纯化方法

    Affinity purification

    免疫原

    Synthesized peptide derived from the N-terminal region of human Caspase-3

    亚型

    IgG
  • 应用备注

    WB 1:500-1:2000, ELISA 1:40000

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    PBS with 0.02 % sodium azide,0.5 % BSA and 50 % glycerol  pH 7.4.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    Caspase 3 (CASP3)

    别名

    Caspase-3

    背景

    Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin.

    分子量

    32kDa

    基因ID

    836

    UniProt

    P42574

    途径

    Apoptosis, Caspase Cascade in Apoptosis, Sensory Perception of Sound, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Activated T Cell Proliferation
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