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DNMT3B 抗体

This anti-DNMT3B antibody is a 兔 多克隆 antibody detecting DNMT3B in WB, ELISA, IF 和 IHC (p). Suitable for 人 和 小鸡.
产品编号 ABIN5959392
发货至: 中国

Quick Overview for DNMT3B 抗体 (ABIN5959392)

抗原

See all DNMT3B 抗体
DNMT3B (DNA (Cytosine-5-)-Methyltransferase 3 beta (DNMT3B))

适用

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人, 小鸡

宿主

  • 92
  • 7
  • 2
  • 1

克隆类型

  • 85
  • 17
多克隆

标记

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This DNMT3B antibody is un-conjugated

应用范围

  • 83
  • 40
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Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 特异性

    Cytosine 5methyltransferase 3B,DNA,DNA (cytosine 5) methyltransferase 3 beta,DNA (cytosine 5)-methyltransferase 3B,DNA (cytosine-5)-methyltransferase 3B,DNA methyltransferase HsaIIIB,DNA MTase HsaIIIB,DNM3B,Dnmt3b,EC 2.1.1.37,ICF,ICF1,M.HsaIIIB,MGC124407,RP23-89H14.3

    纯化方法

    Affinity purification

    免疫原

    Synthesized peptide derived from the N-terminal region of human Dnmt3b

    亚型

    IgG
  • 应用备注

    WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:20000

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol,  pH 7.4

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    DNMT3B (DNA (Cytosine-5-)-Methyltransferase 3 beta (DNMT3B))

    别名

    Dnmt3b

    背景

    CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase which is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes primarily to the nucleus and its expression is developmentally regulated. Mutations in this gene cause the immunodeficiency-centromeric instability-facial anomalies (ICF) syndrome. Eight alternatively spliced transcript variants have been described. The full length sequences of variants 4 and 5 have not been determined.

    分子量

    96kDa

    基因ID

    1789

    UniProt

    Q9UBC3
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