RYR2 抗体 (Ser2808)
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Quick Overview for RYR2 抗体 (Ser2808) (ABIN5957596)
抗原
See all RYR2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Ser2808
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特异性
- ARVC2,ARVD2,Cardiac muscle ryanodine receptor,Cardiac muscle ryanodine receptor-calcium release channel,hRYR-2,ryanodine receptor 2 (cardiac),Ryanodine receptor 2,RyR,RYR-2,RyR2,RYR2,Type 2 ryanodine receptor,VTSIP
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纯化方法
- Affinity purification
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免疫原
- Synthesized peptide derived from human RyR-2 around the non-phosphorylation site of Ser2808.
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亚型
- IgG
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应用备注
- WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:5000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- RYR2 (Ryanodine Receptor 2 (Cardiac) (RYR2))
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别名
- RYR2
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背景
- This gene encodes a ryanodine receptor found in cardiac muscle sarcoplasmic reticulum. The encoded protein is one of the components of a calcium channel, composed of a tetramer of the ryanodine receptor proteins and a tetramer of FK506 binding protein 1B proteins, that supplies calcium to cardiac muscle. Mutations in this gene are associated with stress-induced polymorphic ventricular tachycardia and arrhythmogenic right ventricular dysplasia.RYR2 (Ryanodine Receptor 2) is a Protein Coding gene. Diseases associated with RYR2 include Ventricular Tachycardia, Catecholaminergic Polymorphic, 1 and Arrhythmogenic Right Ventricular Dysplasia 2. Among its related pathways are Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds and Cell-type Dependent Selectivity of CCK2R Signaling. GO annotations related to this gene include calcium ion binding and protein kinase binding. An important paralog of this gene is RYR3.
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分子量
- 564kDa
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基因ID
- 6262
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UniProt
- Q92736
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途径
- Myometrial Relaxation and Contraction
抗原
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