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RYR2 抗体 (Ser2808)

This anti-RYR2 antibody is a 兔 多克隆 antibody detecting RYR2 in ELISA, WB, IF 和 IHC (p). Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN5957596
发货至: 中国

Quick Overview for RYR2 抗体 (Ser2808) (ABIN5957596)

抗原

See all RYR2 抗体
RYR2 (Ryanodine Receptor 2 (Cardiac) (RYR2))

适用

  • 32
  • 18
  • 18
  • 3
人, 小鼠, 大鼠

宿主

  • 30
  • 2

克隆类型

  • 30
  • 2
多克隆

标记

  • 21
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This RYR2 antibody is un-conjugated

应用范围

  • 15
  • 14
  • 13
  • 9
  • 5
  • 5
  • 5
  • 2
  • 2
ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 13
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Ser2808

    特异性

    ARVC2,ARVD2,Cardiac muscle ryanodine receptor,Cardiac muscle ryanodine receptor-calcium release channel,hRYR-2,ryanodine receptor 2 (cardiac),Ryanodine receptor 2,RyR,RYR-2,RyR2,RYR2,Type 2 ryanodine receptor,VTSIP

    纯化方法

    Affinity purification

    免疫原

    Synthesized peptide derived from human RyR-2 around the non-phosphorylation site of Ser2808.

    亚型

    IgG
  • 应用备注

    WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:5000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    RYR2 (Ryanodine Receptor 2 (Cardiac) (RYR2))

    别名

    RYR2

    背景

    This gene encodes a ryanodine receptor found in cardiac muscle sarcoplasmic reticulum. The encoded protein is one of the components of a calcium channel, composed of a tetramer of the ryanodine receptor proteins and a tetramer of FK506 binding protein 1B proteins, that supplies calcium to cardiac muscle. Mutations in this gene are associated with stress-induced polymorphic ventricular tachycardia and arrhythmogenic right ventricular dysplasia.RYR2 (Ryanodine Receptor 2) is a Protein Coding gene. Diseases associated with RYR2 include Ventricular Tachycardia, Catecholaminergic Polymorphic, 1 and Arrhythmogenic Right Ventricular Dysplasia 2. Among its related pathways are Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds and Cell-type Dependent Selectivity of CCK2R Signaling. GO annotations related to this gene include calcium ion binding and protein kinase binding. An important paralog of this gene is RYR3.

    分子量

    564kDa

    基因ID

    6262

    UniProt

    Q92736

    途径

    Myometrial Relaxation and Contraction
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