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TYK2 抗体 (Tyr1054)

This anti-TYK2 antibody is a 兔 多克隆 antibody detecting TYK2 in WB, ELISA, IF 和 IHC (p). Suitable for 人, 小鼠 和 猴.
产品编号 ABIN5957298
发货至: 中国

Quick Overview for TYK2 抗体 (Tyr1054) (ABIN5957298)

抗原

See all TYK2 抗体
TYK2 (Tyrosine Kinase 2 (TYK2))

适用

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人, 小鼠, 猴

宿主

  • 76
  • 12

克隆类型

  • 76
  • 13
多克隆

标记

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  • 1
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This TYK2 antibody is un-conjugated

应用范围

  • 69
  • 34
  • 21
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  • 10
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Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 17
    • 15
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    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
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    • 1
    • 1
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Tyr1054

    特异性

    JTK 1,JTK1,Non receptor tyrosine protein kinase 2,Non receptor tyrosine protein kinase TYK2,Non-receptor tyrosine-protein kinase TYK2,OTTHUMP00000232745,OTTHUMP00000232746,OTTHUMP00000232748,Protein Tyrosine Kinase 2,TYK 2,Tyk2,TYK2,Tyrosine kinase 2

    纯化方法

    Affinity purification

    免疫原

    Synthesized peptide derived from human Tyk 2 around the non-phosphorylation site of Tyr1054.

    亚型

    IgG
  • 应用备注

    WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:10000

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol,  pH 7.4

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    TYK2 (Tyrosine Kinase 2 (TYK2))

    别名

    Tyk 2

    背景

    This gene encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E.TYK2 (Tyrosine Kinase 2) is a Protein Coding gene. Diseases associated with TYK2 include Immunodeficiency 35 and Primary Cutaneous Anaplastic Large Cell Lymphoma. Among its related pathways are Type I Interferon Signaling Pathways and Immune response IFN alpha/beta signaling pathway. GO annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity. An important paralog of this gene is JAK1.

    分子量

    134kDa

    基因ID

    7297

    UniProt

    P29597

    途径

    JAK/STAT Signaling, Hepatitis C
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