IL4 Receptor 抗体 (Tyr497)
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北京 101111
Quick Overview for IL4 Receptor 抗体 (Tyr497) (ABIN5956943)
抗原
See all IL4 Receptor (IL4R) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Tyr497
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特异性
- CD124,IL 4R alpha,IL-4 receptor subunit alpha,IL-4-binding protein,IL-4R subunit alpha,IL-4R-alpha,IL-4RA,IL4-BP,Il4r,IL4R nirs variant 1,IL4RA,IL4RA,Interleukin 4 receptor alpha chain,Interleukin 4 receptor,sIL4Ralpha/prot,Soluble IL-4 receptor subunit alpha,Soluble IL-4R-alpha,Soluble interleukin-4 receptor subunit alpha
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纯化方法
- Affinity purification
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免疫原
- Synthesized peptide derived from human IL-4Ralpha around the non-phosphorylation site of Tyr497.
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亚型
- IgG
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应用备注
- WB 1:500-1:2000, IF 1:100-1:300, ELISA 1:20000
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- IL4 Receptor (IL4R) (Interleukin 4 Receptor (IL4R))
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别名
- IL-4Ralpha
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背景
- Receptor for both interleukin 4 and interleukin 13. Couples to the JAK1/2/3-STAT6 pathway. The IL4 response is involved in promoting Th2 differentiation. The IL4/IL13 responses are involved in regulating IgE production and, chemokine and mucus production at sites of allergic inflammmation. In certain cell types, can signal through activation of insulin receptor substrates, IRS1/IRS2.Soluble IL4R (sIL4R) inhibits IL4-mediated cell proliferation and IL5 up-regulation by T-cells.
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分子量
- 90kDa
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基因ID
- 3566
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UniProt
- P24394
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途径
- JAK/STAT Signaling, Positive Regulation of Immune Effector Process
抗原
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