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IL4 Receptor 抗体 (Tyr497)

This anti-IL4 Receptor antibody is a 兔 多克隆 antibody detecting IL4 Receptor in WB, ELISA 和 IF. Suitable for 人 和 小鼠.
产品编号 ABIN5956943
发货至: 中国

Quick Overview for IL4 Receptor 抗体 (Tyr497) (ABIN5956943)

抗原

See all IL4 Receptor (IL4R) 抗体
IL4 Receptor (IL4R) (Interleukin 4 Receptor (IL4R))

适用

  • 66
  • 39
  • 25
人, 小鼠

宿主

  • 81
  • 12
  • 2
  • 2
  • 2
  • 1

克隆类型

  • 85
  • 12
  • 2
多克隆

标记

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  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
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This IL4 Receptor antibody is un-conjugated

应用范围

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  • 14
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  • 13
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  • 3
  • 3
  • 2
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  • 1
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Western Blotting (WB), ELISA, Immunofluorescence (IF)
  • 抗原表位

    • 16
    • 15
    • 8
    • 6
    • 5
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    • 4
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    • 2
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    • 2
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    • 1
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    • 1
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    • 1
    Tyr497

    特异性

    CD124,IL 4R alpha,IL-4 receptor subunit alpha,IL-4-binding protein,IL-4R subunit alpha,IL-4R-alpha,IL-4RA,IL4-BP,Il4r,IL4R nirs variant 1,IL4RA,IL4RA,Interleukin 4 receptor alpha chain,Interleukin 4 receptor,sIL4Ralpha/prot,Soluble IL-4 receptor subunit alpha,Soluble IL-4R-alpha,Soluble interleukin-4 receptor subunit alpha

    纯化方法

    Affinity purification

    免疫原

    Synthesized peptide derived from human IL-4Ralpha around the non-phosphorylation site of Tyr497.

    亚型

    IgG
  • 应用备注

    WB 1:500-1:2000, IF 1:100-1:300, ELISA 1:20000

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol,  pH 7.4

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    IL4 Receptor (IL4R) (Interleukin 4 Receptor (IL4R))

    别名

    IL-4Ralpha

    背景

    Receptor for both interleukin 4 and interleukin 13. Couples to the JAK1/2/3-STAT6 pathway. The IL4 response is involved in promoting Th2 differentiation. The IL4/IL13 responses are involved in regulating IgE production and, chemokine and mucus production at sites of allergic inflammmation. In certain cell types, can signal through activation of insulin receptor substrates, IRS1/IRS2.Soluble IL4R (sIL4R) inhibits IL4-mediated cell proliferation and IL5 up-regulation by T-cells.

    分子量

    90kDa

    基因ID

    3566

    UniProt

    P24394

    途径

    JAK/STAT Signaling, Positive Regulation of Immune Effector Process
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