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PI3K p85 alpha/gamma 抗体 (pTyr199, pTyr467)

PI3K p85a/g 适用: 人, 小鼠, 大鼠, 猴 WB, ELISA, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5956305
发货至: 中国
  • 抗原 See all PI3K p85 alpha/gamma (PI3K p85a/g) products
    PI3K p85 alpha/gamma (PI3K p85a/g) (Phosphoinositide 3 Kinase, p85 alpha/gamma (PI3K p85a/g))
    抗原表位
    • 18
    • 18
    • 1
    • 1
    • 1
    pTyr199, pTyr467
    适用
    • 22
    • 22
    • 22
    • 16
    • 5
    • 1
    人, 小鼠, 大鼠, 猴
    宿主
    • 22
    克隆类型
    • 22
    多克隆
    标记
    • 7
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PI3K p85 alpha/gamma antibody is un-conjugated
    应用范围
    • 22
    • 14
    • 13
    • 13
    • 9
    • 6
    • 5
    • 3
    • 3
    • 2
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    GRB1,p85 alpha,p85,P85A,Phosphatidylinositol 3 kinase associated p 85 alpha,Phosphatidylinositol 3 kinase regulatory 1,Phosphatidylinositol 3 kinase,regulatory subunit,polypeptide 1 (p85 alpha),Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha,Phosphatidylinositol 3-kinase regulatory subunit alpha,Phosphoinositide 3 kinase,regulatory subunit 1 (alpha),PI3 kinase p85 subunit alpha,PI3-kinase regulatory subunit alpha,PI3-kinase subunit p85-alpha,PI3K,PI3K regulatory subunit alpha,Pik3r1,PtdIns 3 kinase p85 alpha,PtdIns-3-kinase regulatory subunit alpha,PtdIns-3-kinase regulatory subunit p85-alpha
    纯化方法
    Affinity purification
    免疫原
    Synthesized peptide derived from human PI 3-kinase p85/p55 around the phosphorylation site of Tyr467/199
    亚型
    IgG
  • 应用备注
    WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:10000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    PI3K p85 alpha/gamma (PI3K p85a/g) (Phosphoinositide 3 Kinase, p85 alpha/gamma (PI3K p85a/g))
    别名
    PI 3 kinase p85 alpha /gamma (PI3K p85a/g 产品)
    背景
    The enzyme phosphatidylinositol 3 kinase (PI3 kinase) is a lipid kinase that generates phosphatidylinositol 3, 4, 5-triphosphate in response to receptor activation in many signal transduction pathways. Class IA PI3Ks exist as a heterodimer of a catalytic 110 kDa (p110) and a regulatory p85 subunit (e.g. p85 alpha). p85 alpha is an adaptor molecule that regulates the activity of the catalytic p110 subunit by binding to phosphorylated receptor tyrosine kinases (RTKs) through its SH2 domain and mediating the interaction between p110 and the plasma membrane. p85 alpha is necessary for insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues.
    分子量
    54+83kDa
    基因ID
    5295
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