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AIF 抗体 (AA 98-609)

Name: AIF 抗体 (AA 98-609)
SKU: ABIN5776052
Availability: OutOfStock

This anti-AIF antibody is a 小鼠单克隆 antibody detecting AIF in WB, ELISA, IF 和 ICC. Suitable for 人.

The cell lysates (40ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human AIFM1 antibody (1:1000). (AIF 抗体 (AA 98-609))

ICC/IF analysis of AIFM1 in Hep3B cells line, stained with DAPI (Blue) for nucleus staining and monoclonal anti-human AIFM1 antibody (1:100) with goat anti-mouse IgG-Alexa fluor 488 conjugate (Green). (AIF 抗体 (AA 98-609))

2 images

产品编号 ABIN5776052

发货至: 中国

Quick Overview for AIF 抗体 (AA 98-609) (ABIN5776052)

抗原

See all AIF (AIFM1) 抗体

AIF (AIFM1) (Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1))

适用

人

宿主

小鼠

克隆类型

单克隆

标记

This AIF antibody is un-conjugated

应用范围

Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

克隆位点

AT22E9

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AA 98-609

原理

Human AIF/AIFM1 antibody

纯化方法

Purified

免疫原

Recombinant human AIFM1 (98-609aa) purified from E. coli

亚型

IgG2a kappa
anti-Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1) (AA 131-230) antibody
AIFM1 适用: 人, 大鼠, 小鼠, Pig WB, ELISA, ICC, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1) antibody
AIFM1 适用: 人, 大鼠, 小鼠, 猴 WB, IHC, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 4E7 unconjugated

anti-Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1) (AA 103-322) antibody
AIFM1 适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1) (AA 334-613) antibody
AIFM1 适用: 人 WB, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated

anti-Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1) (C-Term) antibody
Verified AIFM1 适用: 人, 大鼠, 小鼠, Pig WB, IHC, ELISA, IF 宿主: 山羊 Polyclonal unconjugated

anti-Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1) (AA 183-195) antibody
Verified AIFM1 适用: 人, 小鼠 WB, IHC, ELISA, IF 宿主: 山羊 Polyclonal unconjugated

anti-Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1) (AA 582-613), (C-Term) antibody
AIFM1 适用: 人, 大鼠, 小鼠 WB, IHC, IF, ICC, FACS 宿主: 兔 Polyclonal unconjugated

anti-Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1) (AA 103-612) antibody
AIFM1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1) (C-Term) antibody
AIFM1 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1) (AA 1-613) antibody
AIFM1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated

限制

仅限研究用
状态

Liquid

浓度

1 mg/mL

缓冲液

Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % glycerol

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C,-80 °C

储存方法

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
抗原

AIF (AIFM1) (Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1))

别名

AIF/AIFM1

背景

Apoptosis-inducing factor 1, also known as AIFM1, is a mitochondrial protein that translocates to the nucleus upon induction of apoptosis. AIFM1 has been shown to cause DNA fragmentation and chromatin condensation and to induce the release of cytochrome c and caspase-9 from mitochondria. Bcl-2 overexpression has been shown to prevent the release of AIFM1 from mitochondria, but not to block its apoptogenic activity. Mutations in this gene cause combined oxidative phosphorylation deficiency 6, which results in a severe mitochondrial encephalomyopathy.

NCBI登录号

NP_665811

途径

Apoptosis, Positive Regulation of Endopeptidase Activity, Cell RedoxHomeostasis, Smooth Muscle Cell Migration, Warburg Effect