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Cytokeratin 5 抗体 (AA 1-590)

This anti-Cytokeratin 5 antibody is a 小鼠 单克隆 antibody detecting Cytokeratin 5 in WB, IHC, ELISA, IF, FACS 和 ICC. Suitable for 人.
产品编号 ABIN5776018
发货至: 中国

Quick Overview for Cytokeratin 5 抗体 (AA 1-590) (ABIN5776018)

抗原

See all Cytokeratin 5 (KRT5) 抗体
Cytokeratin 5 (KRT5) (Keratin 5 (KRT5))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This Cytokeratin 5 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS), Immunocytochemistry (ICC)

克隆位点

AT12C4
  • 抗原表位

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    AA 1-590

    免疫原

    Recombinant human KRT5 (1-590aa) purified from E. coli

    亚型

    IgG2a kappa
  • 限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    储存条件

    4 °C,-20 °C,-80 °C

    储存方法

    Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.
  • 抗原

    Cytokeratin 5 (KRT5) (Keratin 5 (KRT5))

    别名

    KRT5

    背景

    Keratin 5, also known as KRT5, K5, or CK5, dimerizes with keratin 14 and forms the intermediate filaments (IF) that make up the cytoskeleton of basal epithelial cells. This protein is involved in several diseases including epidermolysis bullosa simplex and breast and lung cancers. Keratin 5 (and K14) are expressed primarily in basal keratinocytes in the epidermis, specifically in the stratified epithelium lining the skin and digestive tract. Keratin intermediate filaments make up the cytoskeletal scaffold within epithelial cells, which contributes to the cell architecture and provides the cells with the ability to withstand mechanical, and non-mechanical, stresses. K5/K14 keratin pairs are able to undergo extensive bundling due to the non-helical tail of K15 acting as a weak cross-linker at the intermediate filament surface. This bundling increase the elasticity, and therefore the mechanical resilience, of the intermediate filaments.

    NCBI登录号

    NP_000415
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