ING2 抗体 (AA 1-280)
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北京 101111
Quick Overview for ING2 抗体 (AA 1-280) (ABIN5776013)
抗原
See all ING2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-280
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原理
- Human ING2 antibody
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纯化方法
- Purified
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免疫原
- Recombinant human ING2 (1-280aa) purified from E. coli
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亚型
- IgG1b kappa
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % glycerol
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
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- ING2 (Inhibitor of Growth Family, Member 2 (ING2))
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别名
- ING2
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背景
- ING2 is a member of the inhibitor of growth (ING) family. Members of the ING family associate with and modulate the activity of histone acetyltransferase (HAT) and histone deacetylase (HDAC) complexes and function in DNA repair and apoptosis. This protein seems to be involved in p53/TP53 activation and p53/TP53-dependent apoptotic pathways, probably by enhancing acetylation of p53/TP53. Also, It is component of a mSin3A-like corepressor complex, which is probably involved in deacetylation of nucleosomal histones. ING2 activity seems to be modulated by binding to phosphoinositides.
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NCBI登录号
- NP_001555
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途径
- Chromatin Binding, Autophagy, Negative Regulation of intrinsic apoptotic Signaling
抗原
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