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ING2 抗体 (AA 1-280)

This anti-ING2 antibody is a 小鼠 单克隆 antibody detecting ING2 in WB, ELISA, IF 和 ICC. Suitable for 人.
产品编号 ABIN5776013
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for ING2 抗体 (AA 1-280) (ABIN5776013)

抗原

See all ING2 抗体
ING2 (Inhibitor of Growth Family, Member 2 (ING2))

适用

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宿主

  • 27
  • 6
  • 1
小鼠

克隆类型

  • 28
  • 6
单克隆

标记

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This ING2 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

克隆位点

AT39E5
  • 抗原表位

    • 7
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    AA 1-280

    原理

    Human ING2 antibody

    纯化方法

    Purified

    免疫原

    Recombinant human ING2 (1-280aa) purified from E. coli

    亚型

    IgG1b kappa
  • 限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % glycerol

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C,-80 °C

    储存方法

    Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
  • 抗原

    ING2 (Inhibitor of Growth Family, Member 2 (ING2))

    别名

    ING2

    背景

    ING2 is a member of the inhibitor of growth (ING) family. Members of the ING family associate with and modulate the activity of histone acetyltransferase (HAT) and histone deacetylase (HDAC) complexes and function in DNA repair and apoptosis. This protein seems to be involved in p53/TP53 activation and p53/TP53-dependent apoptotic pathways, probably by enhancing acetylation of p53/TP53. Also, It is component of a mSin3A-like corepressor complex, which is probably involved in deacetylation of nucleosomal histones. ING2 activity seems to be modulated by binding to phosphoinositides.

    NCBI登录号

    NP_001555

    途径

    Chromatin Binding, Autophagy, Negative Regulation of intrinsic apoptotic Signaling
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