Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.
抗原
TOLLIP
(Toll Interacting Protein (TOLLIP))
别名
Tollip
背景
Toll interacting protein, also known as Tollip, is an inhibitory adaptor protein within the signaling pathway of IL-1 and Toll-like receptors (TLR). The Toll-like receptors are essential transmembrane signaling receptors of the innate immune system that alert the host to the presence of a microbial invader. Tollip recruits IRAk1 to the IL-1 receptor complex and inhibits IRAk1 phosphorylation and kinase activity.