Vimentin 抗体 (AA 1-466)
Quick Overview for Vimentin 抗体 (AA 1-466) (ABIN5775972)
抗原
See all Vimentin (VIM) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-466
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免疫原
- Recombinant human VIM (1-466aa) purified from E. coli
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亚型
- IgG1 kappa
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.
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- Vimentin (VIM)
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别名
- Vimentin
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背景
- Vimentin is a type III intermediate filament (IF) protein that is expressed in mesenchymal cells. IF proteins are found in all metazoan cells as well as bacteria. IF, along with tubulin-based microtubules and actin-based microfilaments, comprises the cytoskeleton. All IF proteins are expressed in a highly developmentally-regulated fashion, vimentin is the major cytoskeletal component of mesenchymal cells. Because of this, vimentin is often used as a marker of mesenchymally-derived cells or cells undergoing an epithelial-to-mesenchymal transition (EMT) during both normal development and metastaticprogression.
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NCBI登录号
- NP_003371
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途径
- Caspase Cascade in Apoptosis
抗原
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