PGD 抗体 (AA 1-483)
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北京 101111
Quick Overview for PGD 抗体 (AA 1-483) (ABIN5775894)
抗原
See all PGD 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-483
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原理
- Human 6-phosphogluconate Dehydrogenase/PGD antibody
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纯化方法
- Purified
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免疫原
- Recombinant human PGD (1-483aa) purified from E. coli
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亚型
- IgG2b kappa
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % glycerol
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
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- PGD (Phosphogluconate Dehydrogenase (PGD))
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别名
- 6-phosphogluconate Dehydrogenase/PGD
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背景
- PGD (Phosphogluconate dehydrogenas), also known as 6PGD, is a 483 amino acid enzyme that is involved in the pentose phosphate shunt. Pentose is required for nucleic acid biosynthesis and the pentose phosphate cycle is a major source of NADPH. PGD deficiency increases the level of erythrocyte pyruvate kinase (PK) activity and reduces glutathione synthetase (GSH), resulting in hemolysis. Defects in PGD are generally asymptomatic and are inherited in an autosomal dominant fashion.
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NCBI登录号
- NP_002622
抗原
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