Integrin beta 2 抗体 (PE)
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- 抗原 See all Integrin beta 2 (ITGB2) 抗体
- Integrin beta 2 (ITGB2)
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适用
- 人, 犬
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宿主
- 大鼠
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克隆类型
- 单克隆
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标记
- This Integrin beta 2 antibody is conjugated to PE
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应用范围
- Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Blocking Reagent (BR)
- 特异性
- YFC118.3 was clustered at the Fourth International Workshop on Leucocyte Differentiation Antigen (code number N221) as recognizing the CD18 antigen. The CD18 antigen is an integral membrane glycoprotein of 95kD molecular weight - known as the b chain, of the LFA-1 complex. The CD18 antigen is non-covalently linked to CD11a, b, c molecules. The main cellular reactivity of antibody YFC 118.3 is a strong reactivity with Leucocytes (platelets negative). The CD18 Molecule is the receptor for ICAM-1 and is thus important for cell adhesion. YFC118.3 blocks homotypic adhesion and other lymphocyte functions which involve the LFA-1 antigen.
- 纯化方法
- Protein G purified
- 免疫原
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Human neutrophils.
Type of Immunogen: Cells - 亚型
- IgG2b
- Top Product
- Discover our top product ITGB2 Primary Antibody
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- 应用备注
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Approved: Block, Flo (1:1), IHC, IHC-Fr, IP
Usage: The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. Flow Cytometry: Use 10 μL of the suggested working dilution to label 100 μL whole blood or 10^6 cells in 100 μL. Method sheets are available on request. - 说明
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Target Species of Antibody: Human
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Distilled Water.
- 浓度
- Lot specific
- 缓冲液
- Lyophilized, PBS, pH 7.2, 0.09 % sodium azide, 1 % BSA.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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- 抗原
- Integrin beta 2 (ITGB2)
- 别名
- ITGB2 / MAC-1 / CD18 (ITGB2 产品)
- 别名
- CD18 antibody, LAD antibody, LCAMB antibody, LFA-1 antibody, MAC-1 antibody, MF17 antibody, MFI7 antibody, 2E6 antibody, AI528527 antibody, Cd18 antibody, Lfa1 antibody, ITGB2 antibody, itgb2 antibody, itgb2-a antibody, itgb2-b antibody, integrin subunit beta 2 antibody, integrin beta 2 antibody, integrin subunit beta 2 S homeolog antibody, ITGB2 antibody, Itgb2 antibody, itgb2.S antibody
- 背景
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Name/Gene ID: ITGB2
Family: Integrin
Synonyms: ITGB2, CD18 antigen, CD18, Integrin beta chain, beta 2, LCAMB, MAC-1, MFI7, MF17, Integrin beta-2, LAD, LFA-1 - 基因ID
- 3689
- UniProt
- P05107
- 途径
- NF-kappaB Signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation
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