Annexin V 抗体 (Biotin)
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- 抗原 See all Annexin V (ANXA5) 抗体
- Annexin V (ANXA5) (Annexin A5 (ANXA5))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This Annexin V antibody is conjugated to Biotin
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应用范围
- ELISA, Flow Cytometry (FACS)
- 特异性
- Recognizes human Annexin V, a phospholipid binding protein which binds with high affinity and selectivity to phosphatidylserine (PS), in the presence of calcium. The translocation of PS from the cytosolic leaflet to the outer leaflet of the plasma membrane, due to a loss in plasma membrane asymmetry during apoptosis, acts as an in vivo signal for the removal of the dying cell by phagocytosis. Detection of PS using Annexin V therefore provides a reliable diagnostic tool for the indication of early programmed cell death. Annexin V has also been identified as an anticoagulant protein in the blood coagulation cascade, by acting as an inhibitor of prothrombin activation. The presence of antibodies to Annexin V, are associated with systemic lupus erythematosus (SLE), recurrent spontaneous abortions and systemic sclerosis (SSc). Clone VAA-33 has been reported to work in western blotting applications.
- 纯化方法
- Protein G purified
- 免疫原
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Recombinant Annexin V.
Type of Immunogen: Recombinant protein - 亚型
- IgG2a
- Top Product
- Discover our top product ANXA5 Primary Antibody
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- 应用备注
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Approved: ELISA, Flo
Usage: The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. Flow Cytometry: Use 10 μL of the suggested working dilution to label 1x10^6 cells in 100 μL. Method sheets are available on request. - 说明
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Target Species of Antibody: Human
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Tris-buffered saline, 1 % BSA, 0.02 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- 4°C or -20°C, Avoid freeze-thaw cycles.
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- 抗原
- Annexin V (ANXA5) (Annexin A5 (ANXA5))
- 别名
- ANXA5 / Annexin V (ANXA5 产品)
- 背景
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Name/Gene ID: ANXA5
Synonyms: ANXA5, ANX5, Anchorin CII, Calphobindin I, CBP-I, ENX2, PP4, RPRGL3, Lipocortin V, Thromboplastin inhibitor, VAC-alpha, Vascular anticoagulant-alpha, PAP-I, Annexin A5, Annexin V, Annexin-5, Endonexin II - 基因ID
- 308
- UniProt
- P08758
- 途径
- Apoptosis
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