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- 抗原 See all Sacsin (SACS) 抗体
- Sacsin (SACS) (Spastic Ataxia of Charlevoix-Saguenay (Sacsin) (SACS))
- 适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Sacsin antibody is un-conjugated
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应用范围
- ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 纯化方法
- Antigen affinity purified
- 免疫原
- A recombinant human partial protein corresponding to amino acids E3709-L3909 was used as the immunogen for the Sacsin antibody.
- 亚型
- IgG
- Top Product
- Discover our top product SACS Primary Antibody
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anti-Spastic Ataxia of Charlevoix-Saguenay (Sacsin) (SACS) (AA 983-1150) antibody
SACS 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Spastic Ataxia of Charlevoix-Saguenay (Sacsin) (SACS) (AA 3709-3909) antibodySACS 适用: 人, 小鼠, 大鼠 ELISA, IHC, WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal dilution of the Sacsin antibody should be determined by the researcher.\. Western Blot: 0.5-1 μg/mL,IHC (FFPE): 1-2 μg/mL,Direct ELISA: 0.1-0.5 μg/mL
- 限制
- 仅限研究用
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- 缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
- 储存条件
- -20 °C
- 储存方法
- After reconstitution, the Sacsin antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- 抗原
- Sacsin (SACS) (Spastic Ataxia of Charlevoix-Saguenay (Sacsin) (SACS))
- 别名
- Sacsin (SACS 产品)
- 别名
- A230052M14 antibody, DNAJC29 antibody, E130115J16Rik antibody, mKIAA0730 antibody, ARSACS antibody, sacsin antibody, sacsin molecular chaperone antibody, Sacs antibody, SACS antibody
- 背景
- Sacsin also known as DnaJ homolog subfamily C member 29 (DNAJC29) is a protein that in humans is encoded by the SACS gene. This gene consists of nine exons including a gigantic exon spanning more than 12.8k bp. It encodes the sacsin protein, which includes a UBQ region at the N-terminus, a HEPN domain at the C-terminus and a DnaJ region upstream of the HEPN domain. This modular protein is essential for normal mitochondrial network organization. The gene is highly expressed in the central nervous system, also found in skin, skeletal muscles and at low levels in the pancreas. Mutations in this gene result in autosomal recessive spastic ataxia of Charlevoix-Saguenay (ARSACS), a neurodegenerative disorder characterized by early-onset cerebellar ataxia with spasticityand peripheral neuropathy.
- UniProt
- Q9NZJ4
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