TYR 抗体
Quick Overview for TYR 抗体 (ABIN5708030)
抗原
See all TYR 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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纯化方法
- Purified
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纯度
- Protein A affinity chromatography
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免疫原
- Recombinant protein was used as the immunogen for this recombinant Tyrosinase antibody.
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亚型
- IgG kappa
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anti-Tyrosinase (TYR) (AA 1-377) antibody
TYR 适用: 人 WB, IF, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 2A2-F4 unconjugated
anti-Tyrosinase (TYR) (AA 20-340) antibodyTYR 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Tyrosinase (TYR) (AA 486-513) antibodyTYR 适用: 人 WB, IHC, IF, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-Tyrosinase (TYR) (AA 1-377) antibodyTYR 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Tyrosinase (TYR) antibodyTYR 适用: 人, 小鼠, 猴 WB, IHC, IF, ELISA, ICC 宿主: 兔 Polyclonal unconjugated
anti-Tyrosinase (TYR) antibodyTYR 适用: 人 IHC, IF, FACS, StM 宿主: 小鼠 Monoclonal T311 unconjugated
anti-Tyrosinase (TYR) (C-Term) antibodyTYR 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ELISA, ICC 宿主: 兔 Polyclonal unconjugated
anti-Tyrosinase (TYR) (AA 486-513), (C-Term) antibodyTYR 适用: 人 WB, IF, FACS, IHC (p) 宿主: 兔 Polyclonal RB19155 unconjugated
anti-Tyrosinase (TYR) (C-Term) antibodyTYR 适用: 人 WB, IF, FACS, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Tyrosinase (TYR) antibodyTYR 适用: 人 WB, IF, FACS, IHC (p) 宿主: 小鼠 Monoclonal T311 unconjugated
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应用备注
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The stated application concentrations are suggested starting points. Titration of the recombinant Tyrosinase antibody may be required due to differences in protocols and secondary/substrate sensitivity.
1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.\. Immunohistochemistry (FFPE): 0.5-1 μg/mL for 30 min at RT,Prediluted IHC only format: incubate for 30 min at RT (1) -
限制
- 仅限研究用
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the recombinant Tyrosinase antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- TYR (Tyrosinase (TYR))
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别名
- Tyrosinase
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背景
- Recognizes a cluster of proteins between 70-80 kDa, identified as tyrosinase. Occasionally a minor band at 55 kDa is also detected. This mAb shows no cross-reaction with MAGE-1 and tyrosinase-related protein 1, TRP-1/gp75. Tyrosinase is a copper-containing metalloglycoprotein that catalyzes several steps in the melanin pigment biosynthetic pathway, the hydroxylation of tyrosine to L-3,4-dihydroxy-phenylalanine (dopa), and the subsequent oxidation of dopa to dopaquinone. Mutations of the tyrosinase gene occur in various forms of albinism. Tyrosinase is one of the targets for cytotoxic T-cell recognition in melanoma patients. Staining of melanomas with this mAb shows tyrosinase in melanotic as well as amelanotic variants. This mAb is a useful marker for melanocytes and melanomas.
抗原
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