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Recombinant NKX2-1 抗体

This 兔 单克隆 antibody specifically detects NKX2-1 in IHC (p). It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN5708027
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Recombinant NKX2-1 抗体 (ABIN5708027)

抗原

See all NKX2-1 抗体
NKX2-1 (NK2 Homeobox 1 (NKX2-1))

抗体类型

Recombinant Antibody

适用

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人, 小鼠, 大鼠

宿主

  • 65
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克隆类型

  • 77
  • 38
单克隆

标记

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This NKX2-1 antibody is un-conjugated

应用范围

  • 45
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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

质量等级

Carrier-free

克隆位点

NX2-1-1855R
  • 原理

    Recombinant NKX2.1 Antibody / TTF-1 Rabbit Monoclonal (azide and preservative free)

    纯化方法

    Protein A affinity chromatography

    免疫原

    Recombinant protein was used as the immunogen for the recombinant NKX2.1 antibody.

    亚型

    IgG, kappa
  • 应用备注

    Optimal dilution of the recombinant NKX2.1 antibody should be determined by the researcher.

    1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1 mg/mL in 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    4 °C,-20 °C

    储存方法

    Store the recombinant NKX2.1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
  • 抗原

    NKX2-1 (NK2 Homeobox 1 (NKX2-1))

    别名

    NKX2.1

    背景

    NKX2.1/TTF-1 is a member of the NKx2 family of homeodomain transcription factors. It is expressed in epithelial cells of the thyroid gland and the lung. Nuclei from liver, stomach, pancreas, small intestine, colon, kidney, breast, skin, testes, pituitary, prostate, and adrenal glands are unreactive. Anti-NKX2.1 is useful in differentiating primary adenocarcinoma of the lung from metastatic carcinomas originating in the breast, mediastinal germ cell tumors, and malignant mesothelioma. It can also be used to differentiate small cell lung carcinoma from lymphoid infiltrates. Loss of NKX2.1 expression in non-small cell lung carcinoma has been associated with aggressive behavior of such neoplasms. NKX2.1 reactivity is also seen in thyroid malignancies.

    UniProt

    P43699

    途径

    Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Systemic Arterial Blood Pressure by Hormones, Cellular Glucan Metabolic Process, Feeding Behaviour
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