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Recombinant beta Catenin 抗体

This 兔 单克隆 antibody specifically detects beta Catenin in WB, IF, FACS 和 IHC (p). It exhibits reactivity toward 人.
产品编号 ABIN5707937
发货至: 中国
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Our Local Distributor

中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Recombinant beta Catenin 抗体 (ABIN5707937)

抗原

See all beta Catenin (CATNB) 抗体
beta Catenin (CATNB) (Catenin, beta (CATNB))

抗体类型

Recombinant Antibody

适用

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克隆类型

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单克隆

标记

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This beta Catenin antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

质量等级

Carrier-free

克隆位点

CTNNB1-2030R
  • 原理

    Recombinant b-Catenin Antibody (azide and preservative free)

    纯化方法

    Protein A affinity chromatography

    免疫原

    Human protein was used as the immunogen for the recombinant b-Catenin antibody.

    亚型

    IgG, kappa
  • 应用备注

    Titration of the recombinant b-Catenin antibody may be required due to differences in protocols and secondary/substrate sensitivity.

    1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1 mg/mL in 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    4 °C,-20 °C

    储存方法

    Store the recombinant b-Catenin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
  • 抗原

    beta Catenin (CATNB) (Catenin, beta (CATNB))

    别名

    b-Catenin

    背景

    The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. [RefSeq]

    UniProt

    P35222

    途径

    Peptide Hormone Metabolism
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