Recombinant beta Catenin 抗体
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北京 101111
Quick Overview for Recombinant beta Catenin 抗体 (ABIN5707937)
抗原
See all beta Catenin (CATNB) 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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原理
- Recombinant b-Catenin Antibody (azide and preservative free)
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纯化方法
- Protein A affinity chromatography
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免疫原
- Human protein was used as the immunogen for the recombinant b-Catenin antibody.
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亚型
- IgG, kappa
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应用备注
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Titration of the recombinant b-Catenin antibody may be required due to differences in protocols and secondary/substrate sensitivity.
1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the recombinant b-Catenin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- beta Catenin (CATNB) (Catenin, beta (CATNB))
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别名
- b-Catenin
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背景
- The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. [RefSeq]
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UniProt
- P35222
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途径
- Peptide Hormone Metabolism
抗原
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