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CD1a 抗体

CD1a 适用: 人 IHC (p) 宿主: 小鼠 Monoclonal rC1A-711 unconjugated
产品编号 ABIN5707917
发货至: 中国
  • 抗原 See all CD1a 抗体
    CD1a
    适用
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    宿主
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    小鼠
    克隆类型
    • 119
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    单克隆
    标记
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    This CD1a antibody is un-conjugated
    应用范围
    • 98
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    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    Purified
    纯度
    Protein G affinity chromatography
    免疫原
    Full length human CD1a protein was used as the immunogen for this recombinant CD1a antibody.
    克隆位点
    RC1A-711
    亚型
    IgG1 kappa
    Top Product
    Discover our top product CD1a Primary Antibody
  • 应用备注
    The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the recombinant CD1a antibody to be titered up or down for optimal performance.

    1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.\. Immunohistochemistry (FFPE): 0.5-1 μg/mL for 30 min at RT,Prediluted IHC only format: incubate for 30 min at RT (1)

    限制
    仅限研究用
  • 缓冲液
    0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store the recombinant CD1a antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
  • 抗原
    CD1a
    别名
    CD1a (CD1a 产品)
    背景
    CD1 proteins have been demonstrated to restrict T cell response to non-peptide lipid and glycolipid antigens and play a role in non-classical antigen presentation. CD1a is a non-polymorphic MHC Class 1 related cell surface glycoprotein, expressed in association with Beta-2 microglobulin. Anti-CD1a labels Langerhans cell histiocytosis (Histiocytosis X), extranodal histiocytic sarcoma, a subset of T-lymphoblastic lymphoma/leukemia, and interdigitating dendritic cell sarcoma of the lymph node. When combined with antibodies against TTF-1 and CD5, anti-CD1a is useful in distinguishing between pulmonary and thymic neoplasms since CD1a is consistently expressed in thymic lymphocytes in both typical and atypical thymomas, but only focally in 1/6 of thymic carcinomas and not in lymphocytes in pulmonary neoplasms. Anti-CD1a is reported to be a new marker for perivascular epithelial cell tumor (PEComa).
    基因ID
    909
    途径
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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