Recombinant CLIP 抗体 (AA 25-39)
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Quick Overview for Recombinant CLIP 抗体 (AA 25-39) (ABIN5707527)
抗原
抗体类型
适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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抗原表位
- AA 25-39
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原理
- Recombinant ACTH Antibody / CLIP (azide and preservative free)
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序列
- NGAEDESAEA FPLEF
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纯化方法
- Protein A affinity chromatography
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免疫原
- Amino acids 25-39 (NGAEDESAEAFPLEF) of Adrenocorticotropic hormone (CLIP sequence) were used as the immunogen for this ACTH antibody.
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亚型
- IgG, kappa
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anti-Corticotropin-Like Intermediate Peptide (CLIP) (AA 156-176) antibody
CLIP 适用: 人 WB 宿主: 小鼠 Monoclonal ABM52H4 unconjugated
anti-Corticotropin-Like Intermediate Peptide (CLIP) (AA 156-176) antibodyCLIP 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Corticotropin-Like Intermediate Peptide (CLIP) antibodyCLIP 适用: 人 WB 宿主: 小鼠 Monoclonal CLIP-1133 unconjugated
anti-Corticotropin-Like Intermediate Peptide (CLIP) antibodyCLIP 适用: 人 WB 宿主: 小鼠 Monoclonal CLIP-1133 unconjugated
anti-Corticotropin-Like Intermediate Peptide (CLIP) (AA 25-39) antibodyCLIP 适用: 人, 大鼠, 小鼠 IHC (p) 宿主: 兔 Monoclonal CLIP-2040R unconjugated Recombinant Antibody
anti-Corticotropin-Like Intermediate Peptide (CLIP) (AA 25-39) antibodyCarrier-free CLIP 适用: 人 IHC (p) 宿主: 小鼠 Monoclonal ADCT1-1 unconjugated
anti-Corticotropin-Like Intermediate Peptide (CLIP) (AA 25-39) antibodyCLIP 适用: 人 IHC (p) 宿主: 小鼠 Monoclonal ADCT1-1 unconjugated
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应用备注
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The optimal dilution of the recombinant ACTH antibody for each application should be determined by the researcher.
1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the recombinant ACTH antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- CLIP (Corticotropin-Like Intermediate Peptide (CLIP))
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别名
- ACTH / CLIP
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背景
- ACTH (same as Corticotropin) is a 39 amino acid active peptide produced by the anterior pituitary. This mAb is specific to CLIP (aa 17-39 of ACTH) and does not react with Synacthen (aa 1-24 of ACTH). POMC (pro-opiomelanocortin or corticotropin-lipotropin) is a 267 amino acid polypeptide hormone precursor that goes through extensive, tissue-specific posttranslational processing by convertases. POMC is cleaved into ten hormone chains named NPP, ACTH, alpha-MSH (Melanocyte Stimulating Hormone), beta-MSH, gamma-MSH, CLIP (corticotropin-like intermediary peptide), Lipotropin-beta, Lipotropin-gamma, beta-endorphin and Met-enkephalin. ACTH is also produced by cells of immune system (T-cells, B-cells, and macrophages) in response to stimuli associated with stress. Anti-ACTH is a useful marker in classification of pituitary tumors and the study of pituitary disease. It reacts with ACTH-producing cells (corticotrophs). It also may react with other tumors (e.g. some small cell carcinomas of the lung) causing paraneoplastic syndromes by secreting ACTH.
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UniProt
- P01189
抗原
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