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FOXP3 抗体 (N-Term)

This anti-FOXP3 antibody is a 大鼠单克隆 antibody detecting FOXP3 in FACS. Suitable for 小鼠.

产品编号 ABIN5707214

发货至: 中国

Quick Overview for FOXP3 抗体 (N-Term) (ABIN5707214)

抗原

See all FOXP3 抗体

FOXP3 (Forkhead Box P3 (FOXP3))

适用

162
136
61
28
7
3
3
2
2
1
1
1
1

小鼠

宿主

大鼠

克隆类型

单克隆

标记

110
15
11
10
8
4
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
1
1
1

This FOXP3 antibody is un-conjugated

应用范围

137
81
66
52
41
37
30
29
27
18
10
8
7
6
4
3
2
2
2
2
1
1
1

Flow Cytometry (FACS)

克隆位点

SB168a

Discover our top product FOXP3 Primary Antibody

抗原表位
16

15

12

10

7

6

6

5

5

5

4

4

3

3

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
N-Term

特异性

Mouse Foxp3 (Mr ~57 kDa). Does not cross react with Human Foxp3. T regulatory cells (Originally called T suppressor cells) are a subpopulation of T cells. Their major roles are to suppress excess immune response of other cells and to maintain tolerance of self-antigens. Initially, researchers used CD4 and CD25 (IL-2 receptor) to identify T suppress subpopulation and purified CD4+CD25+ T cells were used for T cells Suppression Assay, however some other activated T cells also express CD25.1,2 The most convincible molecular marker of Treg cells is Forkhead box protein 3 (Foxp3) which is expressed in the nucleus.3 Anti-Foxp3 antibodies are now widely applied to identify the roles of Treg cells in the development of many diseases, such as cancer, autoimmune disease, and organ transplantation.4,5,6 Scientists found that the over-activation of Treg cells may cause cancer cells to escape from immune surveillance 5. Conversely, patients with autoimmune diseases such as psoriasis, systemic lupus erythematous (SLE) have relative dysfunction of Foxp3 positive cells.7,8 Immunologists are trying to induce immune tolerance in organ transplantation using Treg cells.6

产品特性

Rat Anti-Mouse Foxp3-UNLB

免疫原

N-terminal recombinant Mouse Foxp3

亚型

IgG2a
anti-Forkhead Box P3 (FOXP3) (AA 190-412) antibody
FOXP3 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Forkhead Box P3 (FOXP3) (C-Term) antibody
Verified FOXP3 适用: 小鼠 FACS, ELISA, IHC, IF 宿主: 山羊 Polyclonal unconjugated

anti-Forkhead Box P3 (FOXP3) (AA 297-431) antibody
FOXP3 适用: 人 FACS, ELISA, IHC 宿主: 小鼠 Monoclonal 4F12A2 unconjugated

anti-Forkhead Box P3 (FOXP3) (AA 191-412) antibody
FOXP3 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Forkhead Box P3 (FOXP3) (C-Term) antibody
Verified FOXP3 适用: 人 WB, FACS, ELISA, IHC, IF, ICC 宿主: 山羊 Polyclonal unconjugated

anti-Forkhead Box P3 (FOXP3) (N-Term) antibody
FOXP3 适用: 人, 小鼠, 大鼠, Cow, Pig, 兔, 马, 犬, 绵羊, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Forkhead Box P3 (FOXP3) (AA 191-412) antibody
FOXP3 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal D1 unconjugated

anti-Forkhead Box P3 (FOXP3) (AA 1-431) antibody
FOXP3 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated

anti-Forkhead Box P3 (FOXP3) antibody (APC)
FOXP3 适用: 人, 小鼠 ICFC 宿主: 小鼠 Monoclonal 3G3 APC

anti-Forkhead Box P3 (FOXP3) (AA 101-431) antibody
FOXP3 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated

应用备注
- Applications: Flow cytometry
- Working Dilutions: Flow Cytometry: FITC conjugate < 1.0 g/106 cells AF647 conjugate < 0.2 g/106 cells
限制

仅限研究用
浓度

1 mg/mL

缓冲液

0.1 mg of purified immunoglobulin in 0.1 mL of borate buffered saline,  pH 8.2. No preservatives or amine-containing buffer salts added

储存液

Without preservative

储存条件

4 °C

储存方法

Store at 2-8°C
抗原

FOXP3 (Forkhead Box P3 (FOXP3))

别名

Foxp3

途径

Chromatin Binding, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation

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