我们推荐在您的浏览器上开启Javascript，以获得最佳效果。

FOXP3 抗体 (N-Term)

Name: FOXP3 抗体 (N-Term)
Brand: antibodies-online
SKU: ABIN5707214
Availability: OutOfStock

FOXP3 适用: 小鼠 FACS 宿主: 大鼠 Monoclonal SB168a unconjugated

产品编号 ABIN5707214

发货至: 中国

Datasheet as PDF

抗原 See all FOXP3 抗体

FOXP3 (Forkhead Box P3 (FOXP3))
抗原表位
16

15

12

10

6

6

6

5

5

4

3

3

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
N-Term
适用
154

130

57

26

6

3

2

2

1

1

1

1

1
小鼠
宿主
110

65

15

2
大鼠
Compatible Secondaries
克隆类型
111

81
单克隆
标记
94

15

11

10

8

4

3

3

3

3

3

3

3

3

3

2

2

2

2

2

2

2

2

2

2

1

1

1
This FOXP3 antibody is un-conjugated
应用范围
121

80

63

39

37

36

27

19

19

16

10

8

7

6

4

3

2

2

2

1

1

1

1
Flow Cytometry (FACS)

特异性

Mouse Foxp3 (Mr ~57 kDa). Does not cross react with Human Foxp3. T regulatory cells (Originally called T suppressor cells) are a subpopulation of T cells. Their major roles are to suppress excess immune response of other cells and to maintain tolerance of self-antigens. Initially, researchers used CD4 and CD25 (IL-2 receptor) to identify T suppress subpopulation and purified CD4+CD25+ T cells were used for T cells Suppression Assay, however some other activated T cells also express CD25.1,2 The most convincible molecular marker of Treg cells is Forkhead box protein 3 (Foxp3) which is expressed in the nucleus.3 Anti-Foxp3 antibodies are now widely applied to identify the roles of Treg cells in the development of many diseases, such as cancer, autoimmune disease, and organ transplantation.4,5,6 Scientists found that the over-activation of Treg cells may cause cancer cells to escape from immune surveillance 5. Conversely, patients with autoimmune diseases such as psoriasis, systemic lupus erythematous (SLE) have relative dysfunction of Foxp3 positive cells.7,8 Immunologists are trying to induce immune tolerance in organ transplantation using Treg cells.6

产品特性

Rat Anti-Mouse Foxp3-UNLB

免疫原

N-terminal recombinant Mouse Foxp3

克隆位点

SB168a

亚型

IgG2a

Top Product

Discover our top product FOXP3 Primary Antibody
anti-Forkhead Box P3 (FOXP3) (AA 190-412) antibody
FOXP3 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Forkhead Box P3 (FOXP3) (C-Term) antibody
Verified FOXP3 适用: 小鼠 FACS, ELISA, IHC, IF 宿主: 山羊 Polyclonal unconjugated

anti-Forkhead Box P3 (FOXP3) (AA 297-431) antibody
FOXP3 适用: 人 FACS, ELISA, IHC 宿主: 小鼠 Monoclonal 4F12A2 unconjugated

anti-Forkhead Box P3 (FOXP3) (AA 191-412) antibody
FOXP3 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Forkhead Box P3 (FOXP3) (C-Term) antibody
Verified FOXP3 适用: 人 WB, FACS, ELISA, IHC, IF, ICC 宿主: 山羊 Polyclonal unconjugated

anti-Forkhead Box P3 (FOXP3) (N-Term) antibody
FOXP3 适用: 人, 小鼠, 大鼠, Cow, Pig, 马, 兔, 犬, 绵羊, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Forkhead Box P3 (FOXP3) (AA 191-412) antibody
FOXP3 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C1 unconjugated

anti-Forkhead Box P3 (FOXP3) (AA 1-431) antibody
FOXP3 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated

anti-Forkhead Box P3 (FOXP3) antibody (APC)
FOXP3 适用: 人, 小鼠 ICFC 宿主: 小鼠 Monoclonal 3G3 APC

anti-Forkhead Box P3 (FOXP3) (AA 101-431) antibody
FOXP3 适用: 人, 小鼠, 大鼠 IHC (p) 宿主: 兔 Polyclonal unconjugated

应用备注
- Applications: Flow cytometry
- Working Dilutions: Flow Cytometry: FITC conjugate < 1.0 g/106 cells AF647 conjugate < 0.2 g/106 cells
限制

仅限研究用
浓度

1 mg/mL

缓冲液

0.1 mg of purified immunoglobulin in 0.1 mL of borate buffered saline,  pH 8.2. No preservatives or amine-containing buffer salts added

储存液

Without preservative

储存条件

4 °C

储存方法

Store at 2-8°C
抗原

FOXP3 (Forkhead Box P3 (FOXP3))

别名

Foxp3 (FOXP3 产品)

途径

Chromatin Binding, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation