ORAI1 抗体
Quick Overview for ORAI1 抗体 (ABIN5706864)
抗原
See all ORAI1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
Supplier Product No.
- 100-401-p17
-
Supplier
- Rockland
-
原理
- ORAI1 Antibody
-
交叉反应 （详细）
- Anti-ORAI-1 antibody is directed against the human ORAI-1.
-
产品特性
- Synonyms: rabbit anti-ORAI-1 Antibody, Calcium release-activated calcium channel protein 1, orai-1, Transmembrane protein 142A, ORAI1, CRACM1, TMEM142A
-
纯化方法
- The product was prepared from monospecific antiserum by delipidation and defibrination.
-
过滤
- Sterile filtered
-
免疫原
-
Immunogen: This whole rabbit serum was prepared by repeated immunizations with a recombinant fusion protein.
Immunogen Type: Recombinant Protein
-
亚型
- IgG
-
-
anti-ORAI Calcium Release-Activated Calcium Modulator 1 (ORAI1) (AA 200-212), (Extracellular) antibody
KO Validated ORAI1 适用: 小鼠 WB, IHC, FACS, IF, LCI, IC 宿主: 兔 Polyclonal unconjugated
anti-ORAI Calcium Release-Activated Calcium Modulator 1 (ORAI1) (AA 1-87) antibodyORAI1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-ORAI Calcium Release-Activated Calcium Modulator 1 (ORAI1) (Internal Region) antibodyVerified ORAI1 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-ORAI Calcium Release-Activated Calcium Modulator 1 (ORAI1) (C-Term) antibodyORAI1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-ORAI Calcium Release-Activated Calcium Modulator 1 (ORAI1) (AA 202-301) antibodyORAI1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-ORAI Calcium Release-Activated Calcium Modulator 1 (ORAI1) (AA 145-173) antibodyORAI1 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-ORAI Calcium Release-Activated Calcium Modulator 1 (ORAI1) (Extracellular) antibodyORAI1 适用: 人 WB, FACS, IF, LCI, IC 宿主: 小鼠 Monoclonal 3F11-D10-B9 unconjugated
anti-ORAI Calcium Release-Activated Calcium Modulator 1 (ORAI1) antibodyORAI1 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-ORAI Calcium Release-Activated Calcium Modulator 1 (ORAI1) (AA 182-231) antibodyORAI1 适用: 人, Pig, 犬, 兔, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-ORAI Calcium Release-Activated Calcium Modulator 1 (ORAI1) (C-Term) antibodyORAI1 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
Application Note: Anti-ORAI-1 has been tested for use in western blotting. Specific conditions for reactivity should be optimized by the end user. Expect bands approximately 32.7 kDa by western blotting in the appropriate cell lysate or extract.
Western Blot Dilution: 1.0 μg/mL
ELISA Dilution: 1.0 μg/well
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
-
Buffer: 0.01 M Sodium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: None
Preservative: 0.01 % (w/v) Sodium Azide -
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
-
有效期
- 12 months
-
-
- ORAI1 (ORAI Calcium Release-Activated Calcium Modulator 1 (ORAI1))
-
别名
- ORAI1
-
背景
- Background: The ORAI-1 gene codes for the calcium release-activated calcium (CRAC) channel subunit in humans. The CRAC channel subunit mediates calcium influx when activated by the calcium sensor, STIM1, following depletion of intracellular calcium stores. CRAC channels are the primary pathway for calcium influx in T-cells and promote the immune response to pathogens through activation of the transcription factor NFAT. Defects in this gene can be a cause of immune dysfunction due to inactivation of T-cells.
-
基因ID
- 84876
-
NCBI登录号
- NP_116179
-
UniProt
- Q96D31
-
途径
- TCR Signaling, BCR Signaling
抗原
-
