RENT1/UPF1 抗体
Quick Overview for RENT1/UPF1 抗体 (ABIN5704268)
抗原
See all RENT1/UPF1 (UPF1) 抗体适用
宿主
克隆类型
标记
应用范围
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免疫原
- UPF1 regulator of nonsense transcripts homolog (yeast)
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亚型
- IgG
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应用备注
- WB : 1:500-1:5000,IHC:1:20-1:200,IF:1:20-1:200,IP:1:200-1:2000
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说明
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HepG2 cells were subjected to SDS PAGE followed by western blot with FNab09270(UPF1 antibody) at dilution of 1:1000
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限制
- 仅限研究用
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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有效期
- 12 months
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- RENT1/UPF1 (UPF1) (UPF1 Regulator of Nonsense Transcripts Homolog (UPF1))
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别名
- UPF1
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背景
- Synonyms:ATP dependent helicase RENT1, FLJ43809, FLJ46894, HUPF1, KIAA0221, NORF1, pNORF1, RENT1, UPF1 Background:This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein is located only in the cytoplasm. When translation ends, it interacts with the protein that is a functional homolog of yeast Upf2p to trigger mRNA decapping. Use of multiple polyadenylation sites has been noted for this gene. Alternative splicing results in multiple transcript variants.
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分子量
- 43kDa
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基因ID
- 5976
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UniProt
- Q92900
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途径
- SARS-CoV-2 Protein Interactome
抗原
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