KEAP1 抗体
Quick Overview for KEAP1 抗体 (ABIN5702287)
抗原
See all KEAP1 抗体适用
宿主
克隆类型
标记
应用范围
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免疫原
- kelch-like ECH-associated protein 1
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亚型
- IgG
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应用备注
- WB : 1:1000-1:10000 IP : 1:200-1:2000 IHC : 1:50-1:200
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说明
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HepG2 cells were subjected to SDS PAGE followed by western blot with FNab04516(KEAP1 antibody) at dilution of 1:2000
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限制
- 仅限研究用
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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有效期
- 12 months
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- KEAP1 (Kelch-Like ECH-Associated Protein 1 (KEAP1))
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别名
- KEAP1
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背景
- Synonyms:Cytosolic inhibitor of Nrf2, INrf2, KEAP1, Kelch like protein 19, KIAA0132, KLHL19 Background:This gene encodes a protein containing KELCH-1 like domains, as well as a BTB/POZ domain. Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus. This interaction results in the expression of the catalytic subunit of gamma-glutamylcysteine synthetase. Two alternatively spliced transcript variants encoding the same isoform have been found for this gene.
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分子量
- 55-70 kDa
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基因ID
- 9817
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UniProt
- Q14145
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途径
- Maintenance of Protein Location
抗原
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