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KEAP1 抗体 (AA 378-486)

This anti-KEAP1 antibody is a 兔 多克隆 antibody detecting KEAP1 in WB, ELISA, IHC 和 IP. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN5702287
发货至: 中国
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Quick Overview for KEAP1 抗体 (AA 378-486) (ABIN5702287)

抗原

See all KEAP1 抗体
KEAP1 (Kelch-Like ECH-Associated Protein 1 (KEAP1))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This KEAP1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)
  • 抗原表位

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    AA 378-486

    原理

    KEAP1 antibody

    免疫原

    Immunogen sequence: 378-486aa

    Immunogen: kelch-like ECH-associated protein 1

    亚型

    IgG
  • 应用备注

    WB : 1:1000-1:10000 IP : 1:200-1:2000 IHC : 1:50-1:200

    说明

    HepG2 cells were subjected to SDS PAGE followed by western blot with FNab04516(KEAP1 antibody) at dilution of 1:2000

    限制

    仅限研究用
  • 缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze / thaw cycles.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months

    有效期

    12 months
  • 抗原

    KEAP1 (Kelch-Like ECH-Associated Protein 1 (KEAP1))

    别名

    KEAP1

    背景

    Synonyms: Kelch-like ECH-associated protein 1|Cytosolic inhibitor of Nrf2 (INrf2)|Kelch-like protein 19|KEAP1|INRF2|KIAA0132|KLHL19

    Background: This gene encodes a protein containing KELCH-1 like domains, as well as a BTB/POZ domain. Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus. This interaction results in the expression of the catalytic subunit of gamma-glutamylcysteine synthetase. Two alternatively spliced transcript variants encoding the same isoform have been found for this gene.

    分子量

    55-70 kDa

    基因ID

    9817

    UniProt

    Q14145

    途径

    Maintenance of Protein Location
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