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BHLHE41 抗体

BHLHE41 适用: 人, 小鼠, 大鼠 WB, ELISA, IP 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5702192
发货至: 中国
  • 抗原 See all BHLHE41 抗体
    BHLHE41 (Basic Helix-Loop-Helix Family, Member E41 (BHLHE41))
    适用
    • 39
    • 20
    • 13
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 30
    • 8
    • 1
    克隆类型
    • 32
    • 7
    多克隆
    标记
    • 23
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This BHLHE41 antibody is un-conjugated
    应用范围
    • 28
    • 18
    • 7
    • 4
    • 4
    • 4
    • 1
    Western Blotting (WB), ELISA, Immunoprecipitation (IP)
    免疫原
    basic helix-loop-helix family, member e41
    亚型
    IgG
    Top Product
    Discover our top product BHLHE41 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 缓冲液
    PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze / thaw cycles.
    储存条件
    -20 °C
    有效期
    12 months
  • 抗原
    BHLHE41 (Basic Helix-Loop-Helix Family, Member E41 (BHLHE41))
    别名
    BHLHE41 (BHLHE41 产品)
    别名
    BHLHB3 antibody, dec2 antibody, bhlhb3 antibody, sharp1 antibody, sharp-1 antibody, MGC108143 antibody, DEC2 antibody, SHARP1 antibody, hDEC2 antibody, 6430520M22Rik antibody, Bhlhb2l antibody, Bhlhb3 antibody, Sharp1 antibody, Dec2 antibody, SHARP-1 antibody, basic helix-loop-helix family member e41 antibody, basic helix-loop-helix family, member e41 antibody, BHLHE41 antibody, bhlhe41 antibody, Bhlhe41 antibody
    背景
    Synonyms:BHLHB3, DEC2, SHARP1 Background:Transcriptional repressor involved in the regulation of the circadian rhythm by negatively regulating the activity of the clock genes and clock-controlled genes. Acts as the negative limb of a novel autoregulatory feedback loop(DEC loop) which differs from the one formed by the PER and CRY transcriptional repressors(PER/CRY loop). Both these loops are interlocked as it represses the expression of PER1 and in turn is repressed by PER1/2 and CRY1/2. Represses the activity of the circadian transcriptional activator: CLOCK-ARNTL/BMAL1 heterodimer by competing for the binding to E-box elements(5'-CACGTG-3') found within the promoters of its target genes. Negatively regulates its own expression and the expression of DBP and BHLHE41/DEC2. Acts as a corepressor of RXR and the RXR-LXR heterodimers and represses the ligand-induced RXRA/B/G, NR1H3/LXRA, NR1H4 and VDR transactivation activity.
    分子量
    51 kDa,75 kDa
    基因ID
    79365
    UniProt
    Q9C0J9
    途径
    Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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