BHLHE41 抗体
Quick Overview for BHLHE41 抗体 (ABIN5702192)
抗原
See all BHLHE41 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- BHLHE41 antibody
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免疫原
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Immunogen sequence: 419-482
Immunogen: basic helix-loop-helix family, member e41
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亚型
- IgG
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anti-Basic Helix-Loop-Helix Family, Member E41 (BHLHE41) (AA 203-282) antibody
BHLHE41 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4H6 unconjugated
anti-Basic Helix-Loop-Helix Family, Member E41 (BHLHE41) (N-Term) antibodyBHLHE41 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Basic Helix-Loop-Helix Family, Member E41 (BHLHE41) (AA 185-285) antibodyBHLHE41 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Basic Helix-Loop-Helix Family, Member E41 (BHLHE41) (AA 203-282) antibodyBHLHE41 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Basic Helix-Loop-Helix Family, Member E41 (BHLHE41) (AA 1-50) antibodyBHLHE41 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Basic Helix-Loop-Helix Family, Member E41 (BHLHE41) (N-Term) antibodyBHLHE41 适用: 人, 小鼠, 大鼠, 犬, 豚鼠, 马, Pig, 猴, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-Basic Helix-Loop-Helix Family, Member E41 (BHLHE41) (AA 216-265) antibodyBHLHE41 适用: 人, 犬, Cow WB 宿主: 兔 Polyclonal unconjugated
anti-Basic Helix-Loop-Helix Family, Member E41 (BHLHE41) (AA 120-280) antibodyBHLHE41 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Basic Helix-Loop-Helix Family, Member E41 (BHLHE41) (N-Term) antibodyBHLHE41 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- BHLHE41 (Basic Helix-Loop-Helix Family, Member E41 (BHLHE41))
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别名
- BHLHE41
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背景
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Synonyms: Class E basic helix-loop-helix protein 41 (bHLHe41)|Class B basic helix-loop-helix protein 3 (bHLHb3)|Differentially expressed in chondrocytes protein 2 (hDEC2)|Enhancer-of-split and hairy-related protein 1 (SHARP-1)|BHLHE41|BHLHB3|DEC2|SHARP1
Background: Transcriptional repressor involved in the regulation of the circadian rhythm by negatively regulating the activity of the clock genes and clock-controlled genes. Acts as the negative limb of a novel autoregulatory feedback loop(DEC loop) which differs from the one formed by the PER and CRY transcriptional repressors(PER/CRY loop). Both these loops are interlocked as it represses the expression of PER1 and in turn is repressed by PER1/2 and CRY1/2. Represses the activity of the circadian transcriptional activator: CLOCK-ARNTL/BMAL1 heterodimer by competing for the binding to E-box elements(5'-CACGTG-3') found within the promoters of its target genes. Negatively regulates its own expression and the expression of DBP and BHLHE41/DEC2. Acts as a corepressor of RXR and the RXR-LXR heterodimers and represses the ligand-induced RXRA/B/G, NR1H3/LXRA, NR1H4 and VDR transactivation activity.
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分子量
- 51 kDa,75 kDa
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基因ID
- 79365
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UniProt
- Q9C0J9
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途径
- Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
抗原
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