电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

SPOP-B 抗体

SPOP-B 适用: 人, 小鼠, 大鼠 WB, ELISA, IP 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5701294
发货至: 中国
  • 抗原 See all SPOP-B 抗体
    SPOP-B (Speckle-Type POZ Protein (SPOP-B))
    适用
    • 53
    • 18
    • 14
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 52
    • 4
    克隆类型
    • 52
    • 4
    多克隆
    标记
    • 26
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SPOP-B antibody is un-conjugated
    应用范围
    • 44
    • 20
    • 13
    • 13
    • 6
    • 3
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunoprecipitation (IP)
    免疫原
    speckle-type POZ protein
    亚型
    IgG
    Top Product
    Discover our top product SPOP-B Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 缓冲液
    PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze / thaw cycles.
    储存条件
    -20 °C
    有效期
    12 months
  • 抗原
    SPOP-B (Speckle-Type POZ Protein (SPOP-B))
    别名
    SPOP (SPOP-B 产品)
    背景
    Synonyms:HIB homolog 1, Roadkill homolog 1, speckle type POZ protein, SPOP, TEF2 Background:Component of a cullin-RING-based BCR(BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex that mediates the ubiquitination of target proteins, leading most often to their proteasomal degradation. In complex with CUL3, involved in ubiquitination and proteasomal degradation of BRMS1, DAXX, PDX1/IPF1, GLI2 and GLI3. In complex with CUL3, involved in ubiquitination of H2AFY and BMI1, this does not lead to their proteasomal degradation. Inhibits transcriptional activation of PDX1/IPF1 targets, such as insulin, by promoting PDX1/IPF1 degradation. The cullin-RING-based BCR(BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex containing homodimeric SPOP has higher ubiquitin ligase activity than the complex that contains the heterodimer formed by SPOP and SPOPL.
    基因ID
    8405
    UniProt
    O43791
You are here:
客服