BACE1 抗体 (AA 150-457)
Quick Overview for BACE1 抗体 (AA 150-457) (ABIN5700343)
抗原
See all BACE1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 150-457
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原理
- BACE1 antibody
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免疫原
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Immunogen sequence: 150-457aa
Immunogen: beta-site APP-cleaving enzyme 1
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亚型
- IgG
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab00781(BACE1 antibody) at dilution of 1:500
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限制
- 仅限研究用
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- BACE1 (Beta-secretase 1 (BACE1))
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别名
- BACE1
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背景
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Synonyms: Beta-secretase 1|Aspartyl protease 2 (ASP2, Asp 2)|Beta-site amyloid precursor protein cleaving enzyme 1 (Beta-site APP cleaving enzyme 1)|Memapsin-2|Membrane-associated aspartic protease 2|BACE1|BACE|KIAA1149
Background: Responsible for the proteolytic processing of the amyloid precursor protein(APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase.
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分子量
- 70-75 kDa
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基因ID
- 23621
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UniProt
- P56817
抗原
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